Mitochondrial evolution
MW Gray - Cold Spring Harbor perspectives in biology, 2012 - cshperspectives.cshlp.org
Viewed through the lens of the genome it contains, the mitochondrion is of unquestioned
bacterial ancestry, originating from within the bacterial phylum α-Proteobacteria …
bacterial ancestry, originating from within the bacterial phylum α-Proteobacteria …
Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution
Unicellular flagellates of the family Trypanosomatidae are obligatory parasites of
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …
Pathogenesis of chagas' disease: parasite persistence and autoimmunity
ARL Teixeira, MM Hecht, MC Guimaro… - Clinical microbiology …, 2011 - Am Soc Microbiol
Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes
INTRODUCTION Ribosomes are universally conserved assemblies composed of ribosomal
RNA (rRNA) and proteins, where rRNA plays key structural and functional roles. Despite …
RNA (rRNA) and proteins, where rRNA plays key structural and functional roles. Despite …
Comprehensive sub-mitochondrial protein map of the parasitic protist Trypanosoma brucei defines critical features of organellar biology
We have generated a high-confidence mitochondrial proteome (MitoTag) of the
Trypanosoma brucei procyclic stage containing 1,239 proteins. For 337 of these, a …
Trypanosoma brucei procyclic stage containing 1,239 proteins. For 337 of these, a …
Mosaic nature of the mitochondrial proteome: Implications for the origin and evolution of mitochondria
MW Gray - Proceedings of the National Academy of …, 2015 - National Acad Sciences
Comparative studies of the mitochondrial proteome have identified a conserved core of
proteins descended from the α-proteobacterial endosymbiont that gave rise to the …
proteins descended from the α-proteobacterial endosymbiont that gave rise to the …
How a neutral evolutionary ratchet can build cellular complexity
Complex cellular machines and processes are commonly believed to be products of
selection, and it is typically understood to be the job of evolutionary biologists to show how …
selection, and it is typically understood to be the job of evolutionary biologists to show how …
The double‐edged sword in pathogenic trypanosomatids: the pivotal role of mitochondria in oxidative stress and bioenergetics
RFS Menna-Barreto… - BioMed research …, 2014 - Wiley Online Library
The pathogenic trypanosomatids Trypanosoma brucei, Trypanosoma cruzi, and Leishmania
spp. are the causative agents of African trypanosomiasis, Chagas disease, and …
spp. are the causative agents of African trypanosomiasis, Chagas disease, and …
Charting organellar importomes by quantitative mass spectrometry
CD Peikert, J Mani, M Morgenstern, S Käser… - Nature …, 2017 - nature.com
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein
translocation machineries. Analysing whether a protein is transported into an organelle is …
translocation machineries. Analysing whether a protein is transported into an organelle is …
A comprehensive analysis of Trypanosoma brucei mitochondrial proteome
AK Panigrahi, Y Ogata, A Zíková, A Anupama… - …, 2009 - Wiley Online Library
The composition of the large, single, mitochondrion (mt) of Trypanosoma brucei was
characterized by MS (2‐D LC‐MS/MS and gel‐LC‐MS/MS) analyses. A total of 2897 …
characterized by MS (2‐D LC‐MS/MS and gel‐LC‐MS/MS) analyses. A total of 2897 …