Sphingolipids in host–microbial interactions
Highlights•Sphingolipid production is phylogenetically restricted in Bacteria to two
phyla.•Sphingolipid-producing bacteria often associate with eukaryotic hosts.•Many bacterial …
phyla.•Sphingolipid-producing bacteria often associate with eukaryotic hosts.•Many bacterial …
Targeting sphingosine-1-phosphate signaling in immune-mediated diseases: beyond multiple sclerosis
T Pérez-Jeldres, M Alvarez-Lobos, J Rivera-Nieves - Drugs, 2021 - Springer
Abstract Sphingosine-1-phosphate (S1P) is a bioactive lipid metabolite that exerts its actions
by engaging 5 G-protein-coupled receptors (S1PR1-S1PR5). S1P receptors are involved in …
by engaging 5 G-protein-coupled receptors (S1PR1-S1PR5). S1P receptors are involved in …
Bacteroides-derived sphingolipids are critical for maintaining intestinal homeostasis and symbiosis
Sphingolipids are structural membrane components and important eukaryotic signaling
molecules. Sphingolipids regulate inflammation and immunity and were recently identified …
molecules. Sphingolipids regulate inflammation and immunity and were recently identified …
[HTML][HTML] Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models
E Mizoguchi, D Low, Y Ezaki, T Okada - Intestinal research, 2020 - synapse.koreamed.org
The specific pathogenesis underlining inflammatory bowel disease (IBD) is very
complicated, and it is further more difficult to clearly explain the pathophysiology of 2 major …
complicated, and it is further more difficult to clearly explain the pathophysiology of 2 major …
Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target
Inflammatory gastrointestinal (GI) diseases and malignancies are associated with growing
morbidity and cancer-related mortality worldwide. GI tumor and inflammatory cells contain …
morbidity and cancer-related mortality worldwide. GI tumor and inflammatory cells contain …
New biologics and small molecules in inflammatory bowel disease: an update
J Sabino, B Verstockt, S Vermeire… - Therapeutic …, 2019 - journals.sagepub.com
Inflammatory bowel disease (IBD) is a spectrum of immune-mediated inflammatory disorders
with a complex multifactorial pathogenesis, where different pathways may predominate in …
with a complex multifactorial pathogenesis, where different pathways may predominate in …
[HTML][HTML] Selective JAK1 inhibitors for the treatment of inflammatory bowel disease
Janus kinase (JAK) inhibitors, also known as jakinibs, are third-generation oral small
molecules that have expanded the therapeutic options for the management of chronic …
molecules that have expanded the therapeutic options for the management of chronic …
Microscopic colitis: Etiopathology, diagnosis, and rational management
Microscopic colitis is an inflammatory bowel disease divided into two subtypes: collagenous
colitis and lymphocytic colitis. With an increasing incidence of microscopic colitis exceeding …
colitis and lymphocytic colitis. With an increasing incidence of microscopic colitis exceeding …
New targets in inflammatory bowel disease therapy: 2021
New targets in inflammatory bowel disease therapy: 2021 : Current Opinion in
Gastroenterology New targets in inflammatory bowel disease therapy: 2021 : Current …
Gastroenterology New targets in inflammatory bowel disease therapy: 2021 : Current …
A recent update on the use of Chinese medicine in the treatment of inflammatory bowel disease
Background Inflammatory bowel disease (IBD) is a chronic idiopathic disease that is
characterized by inflammation of the gastrointestinal tract. Proper management of IBD …
characterized by inflammation of the gastrointestinal tract. Proper management of IBD …