Plasma high density lipoproteins (HDL) are small, dense, protein-rich particles compared
with other lipoprotein classes; roughly half of total HDL mass is accounted for by lipid …

There are several well-documented functions of high-density lipoprotein (HDL) that may
explain the ability of these lipoproteins to protect against atherosclerosis. The best …

Risk of cardiovascular (CV) disease is increased among RA patients. High inflammatory
burden associated with RA appears to be a key driver of the increased cardiovascular risk …

Atherosclerotic plaques impair vascular function and can lead to arterial obstruction and
tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …

A low level of high-density lipoprotein cholesterol (HDL-C) is an important risk factor for
cardiovascular disease. Epidemiological and clinical studies provide evidence that HDL-C …

Since the first discovery of an inverse correlation between high‐density lipoprotein‐
cholesterol (HDL‐C) levels and coronary heart disease in the 1950s the life cycle of HDL, its …

For more than two decades, there has been continuing evidence of lipid oxidation playing a
central role in atherogenesis. The oxidation hypothesis of atherogenesis has evolved to …

In recent studies we demonstrated that systemic levels of protein-bound nitrotyrosine
(NO2Tyr) and myeloperoxidase (MPO), a protein that catalyzes generation of nitrating …

Chronic renal failure (CRF) results in profound lipid disorders, which stem largely from
dysregulation of high-density lipoprotein (HDL) and triglyceride-rich lipoprotein metabolism …

Background—The inflammatory/antiinflammatory properties of HDL were compared with
HDL cholesterol in 2 groups of patients and in age-and sex-matched control subjects …