[HTML][HTML] Purinergic signalling in the cochlea

SM Vlajkovic, PR Thorne - International Journal of Molecular Sciences, 2022 - mdpi.com
The mammalian cochlea is the sensory organ of hearing with a delicate, highly organised
structure that supports unique operating mechanisms. ATP release from the secretory …

Strategies to reduce the risk of platinum containing antineoplastic drug-induced ototoxicity

D Mukherjea, A Dhukhwa, A Sapra… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Cisplatin is a highly effective chemotherapeutic agent against a variety of solid
tumors in adults and in children. Unfortunately, a large percentage of patients suffer …

The dual role of curcumin and ferulic acid in counteracting chemoresistance and cisplatin-induced ototoxicity

F Paciello, AR Fetoni, D Mezzogori, R Rolesi… - Scientific Reports, 2020 - nature.com
Platinum-based agents, such as cisplatin, form the mainstay of currently used
chemotherapeutic regimens for several malignancies; however, the main limitations are …

Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats

MM Anwar, IMI Laila - BMC complementary medicine and therapies, 2022 - Springer
Background Among the most commonly consumed non-steroidal anti-inflammatory drugs
(NSAID) is Diclofenac (Dic), especially in low-income countries due to its high efficiency and …

Applicability of cork as novel modifiers to develop electrochemical sensor for caffeine determination

MKS Monteiro, DR Da Silva, MA Quiroz, VJP Vilar… - Materials, 2020 - mdpi.com
This study aims to investigate the applicability of a hybrid electrochemical sensor composed
of cork and graphite (Gr) for detecting caffeine in aqueous solutions. Raw cork (RAC) and …

Association between caffeine intake from foods and beverages in the diet and hearing loss in United States adults

F **a, Y Ren - Frontiers in Neurology, 2024 - frontiersin.org
Background Hearing loss (HL) is the third most prevalent condition, significantly affecting
individuals and society. Recent research has explored the potential impact of nutrition …

Association of coffee consumption with the prevalence of hearing loss in US adults, NHANES 2003–2006

S Wu, S Zhu, F Mo, X Yuan, Q Zheng, Y Bai… - Public Health …, 2023 - cambridge.org
Objective: This study aims to explore the association between coffee consumption and the
prevalence of hearing loss in American adults based on a national population-based survey …

Dexamethasone treatment of murine auditory hair cells and cochlear explants attenuates tumor necrosis factor-α-initiated apoptotic damage

BC Kang, J Yi, SH Kim, JH Pak, JW Chung - Plos one, 2023 - journals.plos.org
The most common cause of sensorineural hearing loss is damage of auditory hair cells.
Tumor necrosis factor-alpha (TNF-α) is closely associated with sensorineural hearing loss …

A comprehensive review of the effects of caffeine on the auditory and vestibular systems

MA Ghahraman, S Farahani, E Tavanai - Nutritional Neuroscience, 2022 - Taylor & Francis
Coffee, of which caffeine is a critical component, is probably the most frequently used
psychoactive stimulant in the world. The effects of caffeine on the auditory and vestibular …

The Upregulation of IL-1β Induced by Cisplatin Triggers PI3K/AKT/MMP9 Pathway in Pericytes Mediating the Leakage of the Blood Labyrinth Barrier

M Yu, WJ Jiang, M Yu, Z Zhou, M Wang… - Journal of Inflammation …, 2025 - Taylor & Francis
Background Blood–labyrinth barrier (BLB) damage has been recognized as a key
mechanism underlying cisplatin (CDDP)-induced hearing loss. Inflammation within the …