Tobacco use remains the leading preventable cause of death worldwide. In particular,
people with mental illness are disproportionately affected with high smoking prevalence; …

Substance use disorders occur commonly in patients with schizophrenia and dramatically
worsen their overall clinical course. While the exact mechanisms contributing to substance …

Background People with severe mental illnesses such as schizophrenia are three times
more likely to smoke than the wider population, contributing to widening health inequalities …

A meta-analysis of worldwide studies, found by a 10-year literature follow-up and/or by
searching PubMed, was performed. Forty-two studies across 20 nations consistently …

Background Although the association between psychotic illness and cigarette smoking is
well known, the reasons are unclear why people with psychosis are more likely to smoke …

Context Early detection and prospective evaluation of individuals who will develop
schizophrenia or other psychotic disorders are critical to efforts to isolate mechanisms …

Adolescence is an important ontogenetic period that is characterized by behaviors such as
enhanced novelty-seeking, impulsivity, and reward preference, which can give rise to an …

The high rate of co-occurrence of substance use disorders and other psychiatric disorders is
well established. The population of people with co-occurring disorders is heterogeneous …

Rationale Nicotine has been shown in a variety of studies in humans and experimental
animals to improve cognitive function. Nicotinic treatments are being developed as …

The behavioural and cognitive effects of nicotine in schizophrenia have received much
interest in recent years. The rate of smoking in patients with schizophrenia is estimated to be …