Mass spectrometry imaging under ambient conditions

C Wu, AL Dill, LS Eberlin, RG Cooks… - Mass spectrometry …, 2013 - Wiley Online Library
Mass spectrometry imaging (MSI) has emerged as an important tool in the last decade and it
is beginning to show potential to provide new information in many fields owing to its unique …

A concise review of mass spectrometry imaging

ERA van Hove, DF Smith, RMA Heeren - Journal of chromatography A, 2010 - Elsevier
Mass spectrometric imaging allows the investigation of the spatial distribution of molecules
at complex surfaces. The combination of molecular speciation with local analysis renders a …

Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences

RJA Goodwin - Journal of proteomics, 2012 - Elsevier
Mass spectrometry imaging (MSI) enables the direct analysis of molecules from the surface
of a wide variety of samples, allowing the multiplex measurement of both abundance and …

Mass spectrometry imaging for drug distribution studies

B Prideaux, M Stoeckli - Journal of proteomics, 2012 - Elsevier
Since its introduction mass spectrometry imaging (MSI) has proven to be a powerful tool for
the localization of molecules in biological tissues. In drug discovery and development …

Desorption electrospray ionization and other ambient ionization methods: current progress and preview

DR Ifa, C Wu, Z Ouyang, RG Cooks - Analyst, 2010 - pubs.rsc.org
Mass spectrometry allows rapid chemical analysis of untreated samples in the ambient
environment. This is a result of recent rapid progress in ambient ionization techniques. The …

Fully automated liquid extraction‐based surface sampling and ionization using a chip‐based robotic nanoelectrospray platform

V Kertesz, GJ Van Berkel - Journal of mass spectrometry, 2010 - Wiley Online Library
A fully automated liquid extraction‐based surface sampling device utilizing an Advion
NanoMate chip‐based infusion nanoelectrospray ionization system is reported. Analyses …

Imaging mass spectrometry: instrumentation, applications, and combination with other visualization techniques

A Bodzon‐Kulakowska, P Suder - Mass spectrometry reviews, 2016 - Wiley Online Library
Imaging Mass Spectrometry (IMS) is strengthening its position as a valuable analytical tool. It
has unique ability to identify structures and to unravel molecular changes that occur in the …

Mass spectrometry imaging of plant metabolites–principles and possibilities

N Bjarnholt, B Li, J D'Alvise, C Janfelt - Natural product reports, 2014 - pubs.rsc.org
Covering: up to the end of 2013 New mass spectrometry imaging (MSI) techniques are
gaining importance in the analysis of plant metabolite distributions, and significant …

Direct analysis of biological tissue by paper spray mass spectrometry

H Wang, NE Manicke, Q Yang, L Zheng, R Shi… - Analytical …, 2011 - ACS Publications
Paper spray mass spectrometry (PS-MS) is explored as a fast and convenient way for direct
analysis of molecules in tissues with minimum sample pretreatment. This technique allows …

Mass spectrometry imaging and its application in pharmaceutical research and development: A concise review

JG Swales, G Hamm, MR Clench… - International Journal of …, 2019 - Elsevier
Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …