Objective Fracture-related infection (FRI) remains a major concern in orthopaedic trauma.
Functionalizing implants with antibacterial coatings are a promising strategy in mitigating …

Drug delivery platforms have gracefully emerged as an indispensable component of novel
cancer chemotherapy, bestowing targeted drug distribution, elevating therapeutic effects …

Bone nonunion poses an urgent clinical challenge that needs to be addressed. Recent
studies have revealed that the metabolic microenvironment plays a vital role in fracture …

The effective management of osteomyelitis remains extremely challenging due to the
difficulty associated with treating bone defects, the high probability of recurrence, the …

Staphylococcus aureus forms biofilms consisting of cells embedded in a matrix made of
proteins, polysaccharides, lipids, and extracellular DNA (eDNA). Biofilm-associated …

Simple Summary This study assessed the in vitro antibacterial and antibiofilm properties of
bacterial cellulose hydrogel (HYDROGEL) produced by Zoogloea sp. combined with …

Implantable biomedical devices have found widespread use in restoring lost functions or
structures within the human body, but they face a significant challenge from microbial …

The treatment of bone infections still involves systemic or local antibiotic therapy in high
doses for prolonged periods. Current research focuses on the application of different drug …

Osteoporotic bone defects cannot withstand surgery with more significant trauma due to
bone fragility, while systemic drug therapy has formidable adverse effects. Consequently …

Liposomes are the most widespread drug delivery systems due to their unique properties
such as biocompatibility, biodegradability, controlled release of their cargo and cell …