Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Linking cell mechanical memory and cancer metastasis

E Cambria, MF Coughlin, MA Floryan… - Nature Reviews …, 2024 - nature.com
Metastasis causes most cancer-related deaths; however, the efficacy of anti-metastatic drugs
is limited by incomplete understanding of the biological mechanisms that drive metastasis …

[HTML][HTML] Calcium phosphate-based biomaterials for bone repair

X Hou, L Zhang, Z Zhou, X Luo, T Wang… - Journal of functional …, 2022 - mdpi.com
Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

Bone tissue engineering scaffolds: function of multi‐material hierarchically structured scaffolds

TM Koushik, CM Miller… - Advanced healthcare …, 2023 - Wiley Online Library
Bone tissue engineering (BTE) is a topic of interest for the last decade, and advances in
materials, processing techniques, and the understanding of bone healing pathways have …

[HTML][HTML] Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds

G Zhu, T Zhang, M Chen, K Yao, X Huang, B Zhang… - Bioactive materials, 2021 - Elsevier
Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …

The role of natural polymers in bone tissue engineering

L Guo, Z Liang, L Yang, W Du, T Yu, H Tang… - Journal of Controlled …, 2021 - Elsevier
Bone is a dynamic self-healing organ and a continuous remodeling ensures the restoration
of the bone structure and function over time. However, bone remodeling is not able to repair …

Scaffolds for bone-tissue engineering

SS Lee, X Du, I Kim, SJ Ferguson - Matter, 2022 - cell.com
Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …

A review of 3D polymeric scaffolds for bone tissue engineering: principles, fabrication techniques, immunomodulatory roles, and challenges

AG Abdelaziz, H Nageh, SM Abdo, MS Abdalla… - Bioengineering, 2023 - mdpi.com
Over the last few years, biopolymers have attracted great interest in tissue engineering and
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …

[HTML][HTML] Porous scaffolds for bone regeneration

N Abbasi, S Hamlet, RM Love, NT Nguyen - Journal of science: advanced …, 2020 - Elsevier
Globally, bone fractures due to osteoporosis occur every 20 s in people aged over 50 years.
The significant healthcare costs required to manage this problem are further exacerbated by …

3D printing of microenvironment‐specific bioinspired and exosome‐reinforced hydrogel scaffolds for efficient cartilage and subchondral bone regeneration

Q Li, H Yu, F Zhao, C Cao, T Wu, Y Fan… - Advanced …, 2023 - Wiley Online Library
In clinical practice, repairing osteochondral defects presents a challenge due to the varying
biological properties of articular cartilages and subchondral bones. Thus, elucidating how …