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Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions
P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …
Linking cell mechanical memory and cancer metastasis
Metastasis causes most cancer-related deaths; however, the efficacy of anti-metastatic drugs
is limited by incomplete understanding of the biological mechanisms that drive metastasis …
is limited by incomplete understanding of the biological mechanisms that drive metastasis …
[HTML][HTML] Calcium phosphate-based biomaterials for bone repair
X Hou, L Zhang, Z Zhou, X Luo, T Wang… - Journal of functional …, 2022 - mdpi.com
Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …
Bone tissue engineering scaffolds: function of multi‐material hierarchically structured scaffolds
TM Koushik, CM Miller… - Advanced healthcare …, 2023 - Wiley Online Library
Bone tissue engineering (BTE) is a topic of interest for the last decade, and advances in
materials, processing techniques, and the understanding of bone healing pathways have …
materials, processing techniques, and the understanding of bone healing pathways have …
[HTML][HTML] Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds
G Zhu, T Zhang, M Chen, K Yao, X Huang, B Zhang… - Bioactive materials, 2021 - Elsevier
Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …
approaches, autologous and allogeneic bone grafting have not achieved the ideal …
The role of natural polymers in bone tissue engineering
L Guo, Z Liang, L Yang, W Du, T Yu, H Tang… - Journal of Controlled …, 2021 - Elsevier
Bone is a dynamic self-healing organ and a continuous remodeling ensures the restoration
of the bone structure and function over time. However, bone remodeling is not able to repair …
of the bone structure and function over time. However, bone remodeling is not able to repair …
Scaffolds for bone-tissue engineering
Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …
A review of 3D polymeric scaffolds for bone tissue engineering: principles, fabrication techniques, immunomodulatory roles, and challenges
Over the last few years, biopolymers have attracted great interest in tissue engineering and
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …
[HTML][HTML] Porous scaffolds for bone regeneration
Globally, bone fractures due to osteoporosis occur every 20 s in people aged over 50 years.
The significant healthcare costs required to manage this problem are further exacerbated by …
The significant healthcare costs required to manage this problem are further exacerbated by …
3D printing of microenvironment‐specific bioinspired and exosome‐reinforced hydrogel scaffolds for efficient cartilage and subchondral bone regeneration
Q Li, H Yu, F Zhao, C Cao, T Wu, Y Fan… - Advanced …, 2023 - Wiley Online Library
In clinical practice, repairing osteochondral defects presents a challenge due to the varying
biological properties of articular cartilages and subchondral bones. Thus, elucidating how …
biological properties of articular cartilages and subchondral bones. Thus, elucidating how …