Neutrophil heterogeneity and aging: implications for COVID-19 and wound healing

Y Liu, C **ang, Z Que, C Li, W Wang, L Yin… - Frontiers in …, 2023 - frontiersin.org
Neutrophils play a critical role in the immune response to infection and tissue injury.
However, recent studies have shown that neutrophils are a heterogeneous population with …

PDE4 inhibitors for disease therapy: advances and future perspective

B Du, M Luo, C Ren, J Zhang - Future Medicinal Chemistry, 2023 - Taylor & Francis
The PDE4 enzyme family is specifically responsible for hydrolyzing cAMP and plays a vital
role in regulating the balance of second messengers. As a crucial regulator in signal …

Identification of diagnostic biomarkers and therapeutic targets in peripheral immune landscape from coronary artery disease

X Feng, Y Zhang, M Du, S Li, J Ding, J Wang… - Journal of Translational …, 2022 - Springer
Background Peripheral biomarkers are increasingly vital non-invasive methods for
monitoring coronary artery disease (CAD) progression. Their superiority in early detection …

Cutibacterium acnes strains associated with bone prosthesis infections cannot evade the host immune system

L Thoraval, M Tang-Fichaux, C Guillaume… - Frontiers in …, 2024 - frontiersin.org
Introduction Cutibacterium acnes is a commensal skin bacterium that is involved in bone
prosthesis infections (BPIs) and presents low-grade clinical symptoms. C. acnes has been …

Redox-activation of neutrophils induced by pericardium scaffolds

II Vlasova, SK Suleimanov, EV Mikhalchik… - International Journal of …, 2022 - mdpi.com
Implantation of scaffolds causes a local inflammatory response whereby the early
recruitment of neutrophils is of great importance not only for fighting the infection, but also for …

Identification of Endoplasmic Reticulum Stress‐Related Biomarkers in Coronary Artery Disease

Y Lin, L Ni, L Yang, H Li, Z Chen, Y Gao… - Cardiovascular …, 2024 - Wiley Online Library
Coronary artery disease (CAD) is caused by atherosclerotic lesions in the coronary vessels.
Endoplasmic reticulum stress (ERS) acts in cardiovascular disease, and its role in CAD is …