Ecology, evolution and spillover of coronaviruses from bats

M Ruiz-Aravena, C McKee, A Gamble, T Lunn… - Nature Reviews …, 2022 - nature.com
In the past two decades, three coronaviruses with ancestral origins in bats have emerged
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …

Diversity and evolution of the animal virome

E Harvey, EC Holmes - Nature Reviews Microbiology, 2022 - nature.com
The COVID-19 pandemic has given the study of virus evolution and ecology new relevance.
Although viruses were first identified more than a century ago, we likely know less about …

[HTML][HTML] Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses

H Zhou, J Ji, X Chen, Y Bi, J Li, Q Wang, T Hu, H Song… - Cell, 2021 - cell.com
Despite the discovery of animal coronaviruses related to SARS-CoV-2, the evolutionary
origins of this virus are elusive. We describe a meta-transcriptomic study of 411 bat samples …

Pathogen spillover driven by rapid changes in bat ecology

P Eby, AJ Peel, A Hoegh, W Madden, JR Giles… - Nature, 2023 - nature.com
During recent decades, pathogens that originated in bats have become an increasing public
health concern. A major challenge is to identify how those pathogens spill over into human …

[HTML][HTML] Universal coronavirus vaccines—an urgent need

DM Morens, JK Taubenberger… - New England Journal of …, 2022 - Mass Medical Soc
Universal Coronavirus Vaccines—An Urgent Need We need a research approach that can
characterize the global coronaviral universe, characterize the natural history and …

Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential

J Wang, Y Pan, L Yang, W Yang, K Lv, C Luo… - Nature …, 2023 - nature.com
Bats are reservoir hosts for many zoonotic viruses. Despite this, relatively little is known
about the diversity and abundance of viruses within individual bats, and hence the …

[HTML][HTML] The origin of COVID-19 and why it matters

DM Morens, JG Breman, CH Calisher… - The American journal …, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic is among the deadliest infectious diseases to have emerged in
recent history. As with all past pandemics, the specific mechanism of its emergence in …

Petabase-scale sequence alignment catalyses viral discovery

RC Edgar, B Taylor, V Lin, T Altman, P Barbera… - Nature, 2022 - nature.com
Public databases contain a planetary collection of nucleic acid sequences, but their
systematic exploration has been inhibited by a lack of efficient methods for searching this …

SARS-CoV-2 jum** the species barrier: Zoonotic lessons from SARS, MERS and recent advances to combat this pandemic virus

K Dhama, SK Patel, K Sharun, M Pathak… - Travel medicine and …, 2020 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2 (Severe Acute
Respiratory Syndrome-Coronavirus-2) of the family Coronaviridae, appeared in China in …

The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?

RJ Boyton, DM Altmann - Nature Reviews Immunology, 2021 - nature.com
An important challenge during the COVID-19 pandemic has been to understand
asymptomatic disease and the extent to which this may be a source of transmission. As …