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Remap** revisited: how the hippocampus represents different spaces
AA Fenton - Nature Reviews Neuroscience, 2024 - nature.com
The representation of distinct spaces by hippocampal place cells has been linked to
changes in their place fields (the locations in the environment where the place cells …
changes in their place fields (the locations in the environment where the place cells …
[HTML][HTML] Time and experience differentially affect distinct aspects of hippocampal representational drift
Hippocampal activity is critical for spatial memory. Within a fixed, familiar environment,
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …
[HTML][HTML] Mystery of the memory engram: History, current knowledge, and unanswered questions
MR Lopez, SMH Wasberg, CM Gagliardi… - Neuroscience & …, 2024 - Elsevier
The quest to understand the memory engram has intrigued humans for centuries. Recent
technological advances, including genetic labelling, imaging, optogenetic and …
technological advances, including genetic labelling, imaging, optogenetic and …
Retuning of hippocampal representations during sleep
Hippocampal representations that underlie spatial memory undergo continuous refinement
following formation. Here, to track the spatial tuning of neurons dynamically during offline …
following formation. Here, to track the spatial tuning of neurons dynamically during offline …
[HTML][HTML] Perpetual step-like restructuring of hippocampal circuit dynamics
Summary Representation of the environment by hippocampal populations is known to drift
even within a familiar environment, which could reflect gradual changes in single-cell activity …
even within a familiar environment, which could reflect gradual changes in single-cell activity …
Prefrontal cortical ripples mediate top-down suppression of hippocampal reactivation during sleep memory consolidation
Consolidation of initially encoded hippocampal representations in the neocortex through
reactivation is crucial for long-term memory formation and is facilitated by the coordination of …
reactivation is crucial for long-term memory formation and is facilitated by the coordination of …
Temporal information in the anterior cingulate cortex relates to accumulated experiences
Anterior cingulate cortex (ACC) activity is important for operations that require the ability to
integrate multiple experiences over time, such as rule learning, cognitive flexibility, working …
integrate multiple experiences over time, such as rule learning, cognitive flexibility, working …
[HTML][HTML] Adult-born granule cells facilitate remap** of spatial and non-spatial representations in the dentate gyrus
Adult-born granule cells (abGCs) have been implicated in memory discrimination through a
neural computation known as pattern separation. Here, using in vivo Ca 2+ imaging, we …
neural computation known as pattern separation. Here, using in vivo Ca 2+ imaging, we …
Dynamic and selective engrams emerge with memory consolidation
Episodic memories are encoded by experience-activated neuronal ensembles that remain
necessary and sufficient for recall. However, the temporal evolution of memory engrams …
necessary and sufficient for recall. However, the temporal evolution of memory engrams …
Representational drift as a result of implicit regularization
Recent studies show that, even in constant environments, the tuning of single neurons
changes over time in a variety of brain regions. This representational drift has been …
changes over time in a variety of brain regions. This representational drift has been …