Remap** revisited: how the hippocampus represents different spaces

AA Fenton - Nature Reviews Neuroscience, 2024 - nature.com
The representation of distinct spaces by hippocampal place cells has been linked to
changes in their place fields (the locations in the environment where the place cells …

[HTML][HTML] Time and experience differentially affect distinct aspects of hippocampal representational drift

N Geva, D Deitch, A Rubin, Y Ziv - Neuron, 2023 - cell.com
Hippocampal activity is critical for spatial memory. Within a fixed, familiar environment,
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …

[HTML][HTML] Mystery of the memory engram: History, current knowledge, and unanswered questions

MR Lopez, SMH Wasberg, CM Gagliardi… - Neuroscience & …, 2024 - Elsevier
The quest to understand the memory engram has intrigued humans for centuries. Recent
technological advances, including genetic labelling, imaging, optogenetic and …

Retuning of hippocampal representations during sleep

K Maboudi, B Giri, H Miyawaki, C Kemere, K Diba - Nature, 2024 - nature.com
Hippocampal representations that underlie spatial memory undergo continuous refinement
following formation. Here, to track the spatial tuning of neurons dynamically during offline …

[HTML][HTML] Perpetual step-like restructuring of hippocampal circuit dynamics

ZS Zheng, R Huszár, T Hainmueller, M Bartos… - Cell reports, 2024 - cell.com
Summary Representation of the environment by hippocampal populations is known to drift
even within a familiar environment, which could reflect gradual changes in single-cell activity …

Prefrontal cortical ripples mediate top-down suppression of hippocampal reactivation during sleep memory consolidation

JD Shin, SP Jadhav - Current biology, 2024 - cell.com
Consolidation of initially encoded hippocampal representations in the neocortex through
reactivation is crucial for long-term memory formation and is facilitated by the coordination of …

Temporal information in the anterior cingulate cortex relates to accumulated experiences

RA Wirt, TK Soluoku, RM Ricci, JK Seamans… - Current Biology, 2024 - cell.com
Anterior cingulate cortex (ACC) activity is important for operations that require the ability to
integrate multiple experiences over time, such as rule learning, cognitive flexibility, working …

[HTML][HTML] Adult-born granule cells facilitate remap** of spatial and non-spatial representations in the dentate gyrus

SN Tuncdemir, AD Grosmark, H Chung, VM Luna… - Neuron, 2023 - cell.com
Adult-born granule cells (abGCs) have been implicated in memory discrimination through a
neural computation known as pattern separation. Here, using in vivo Ca 2+ imaging, we …

Dynamic and selective engrams emerge with memory consolidation

DF Tomé, Y Zhang, T Aida, O Mosto, Y Lu… - Nature …, 2024 - nature.com
Episodic memories are encoded by experience-activated neuronal ensembles that remain
necessary and sufficient for recall. However, the temporal evolution of memory engrams …

Representational drift as a result of implicit regularization

A Ratzon, D Derdikman, O Barak - Elife, 2024 - elifesciences.org
Recent studies show that, even in constant environments, the tuning of single neurons
changes over time in a variety of brain regions. This representational drift has been …