[HTML][HTML] Interferon-stimulated genes as enhancers of antiviral innate immune signaling
The ability of a host to curb a viral infection is heavily reliant on the effectiveness of an initial
antiviral innate immune response, resulting in the upregulation of interferon (IFN) and …
antiviral innate immune response, resulting in the upregulation of interferon (IFN) and …
Direct antiviral mechanisms of interferon-gamma
Interferon-gamma (IFNG) is a pleiotropic cytokine that modulates both innate and adaptive
immune networks; it is the most potent activator of macrophages and a signature cytokine of …
immune networks; it is the most potent activator of macrophages and a signature cytokine of …
Sex differences and immune correlates of Long Covid development, symptom persistence, and resolution
RE Hamlin, SM Pienkos, L Chan, MA Stabile… - Science Translational …, 2024 - science.org
Sex differences have been observed in acute coronavirus disease 2019 (COVID-19) and
Long Covid (LC) outcomes, with greater disease severity and mortality during acute infection …
Long Covid (LC) outcomes, with greater disease severity and mortality during acute infection …
microRNA-122 amplifies hepatitis C virus translation by sha** the structure of the internal ribosomal entry site
Abstract The liver-specific microRNA-122 (miR-122) recognizes two conserved sites at the
5′ end of the hepatitis C virus (HCV) genome and contributes to stability, translation, and …
5′ end of the hepatitis C virus (HCV) genome and contributes to stability, translation, and …
DEAD/H-box helicases: Anti-viral and pro-viral roles during infections
R Ullah, J Li, P Fang, S **ao, L Fang - Virus Research, 2022 - Elsevier
Abstract DEAD/H-box RNA helicases make the prominent family of helicases super family-2
which take part in almost all RNA-related processes, from initiation of transcription to RNA …
which take part in almost all RNA-related processes, from initiation of transcription to RNA …
DEAD-box helicases: sensors, regulators, and effectors for antiviral defense
F Taschuk, S Cherry - Viruses, 2020 - mdpi.com
DEAD-box helicases are a large family of conserved RNA-binding proteins that belong to
the broader group of cellular DExD/H helicases. Members of the DEAD-box helicase family …
the broader group of cellular DExD/H helicases. Members of the DEAD-box helicase family …
DExD/H-box helicases: multifunctional regulators in antiviral innate immunity
C Su, Y Tang, C Zheng - Cellular and Molecular Life Sciences, 2022 - Springer
DExD/H-box helicases play critical roles in multiple cellular processes, including
transcription, cellular RNA metabolism, translation, and infections. Several seminal studies …
transcription, cellular RNA metabolism, translation, and infections. Several seminal studies …
DExH/D-box helicases at the frontline of intrinsic and innate immunity against viral infections
B Bonaventure, C Goujon - Journal of General Virology, 2022 - microbiologyresearch.org
DExH/D-box helicases are essential nucleic acid and ribonucleoprotein remodelers
involved in all aspects of nucleic acid metabolism including replication, gene expression …
involved in all aspects of nucleic acid metabolism including replication, gene expression …
Comparative analysis of African and Asian lineage-derived Zika virus strains reveals differences in activation of and sensitivity to antiviral innate immunity
In recent years, Asian lineage Zika virus (ZIKV) strains emerged to cause pandemic
outbreaks associated with a high rate of congenital ZIKV syndrome (CZVS). The reasons for …
outbreaks associated with a high rate of congenital ZIKV syndrome (CZVS). The reasons for …
Multi–cell type gene coexpression network analysis reveals coordinated interferon response and cross–cell type correlations in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an incurable autoimmune disease disproportionately
affecting women. A major obstacle in finding targeted therapies for SLE is its remarkable …
affecting women. A major obstacle in finding targeted therapies for SLE is its remarkable …