The linear peptide gramicidin forms prototypical ion channels specific for monovalent
cations and has been extensively used to study the organization, dynamics and function of …

Transport of ions through pores in membranes is a process of fundamental importance to
cell biology. In living organisms, such transport is facilitated by ion channels that utilize the …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

The mechanism (s) underlying the sorting of integral membrane proteins between the Golgi
complex and the plasma membrane remain uncertain because no specific Golgi retention …

Amoebapore A is a 77-residue protein from the protozoan parasite and human pathogen
Entamoeba histolytica. Amoebapores lyse both bacteria and eukaryotic cells by pore …

The amphipathic α-helix is a common motif found in many cell lytic peptides including
antimicrobial peptides. We have recently shown that significantly altering the amphipathic …

Planar systems–monolayers and films–constitute a useful platform for studying membrane-
active peptides. Here, we summarize varied approaches for studying peptide organization …

Water molecules play a key role in all biochemical processes. They help define the shape of
proteins, and they are reactant or product in many reactions and are released as ligands are …

Membrane and membrane-active peptides and proteins play a crucial role in numerous cell
processes, such as signaling, ion conductance, fusion, and others. Many of them act as …

Hydrophobic mismatch which is defined as the difference between the lipid hydrophobic
thickness and the peptide hydrophobic length is known to be responsible in altering the …