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Dengue: update on clinically relevant therapeutic strategies and vaccines
Opinion statement Dengue viruses (DENV) continue to circulate worldwide, resulting in a
significant burden on human health. There are four antigenically distinct serotypes of DENV …
significant burden on human health. There are four antigenically distinct serotypes of DENV …
The double burden of diabetes and global infection in low and middle-income countries
Four out of five people in the world with diabetes now live in low-and middle-income
countries (LMIC), and the incidence of diabetes is accelerating in poorer communities …
countries (LMIC), and the incidence of diabetes is accelerating in poorer communities …
The role of host cholesterol during flavivirus infection
In recent years the emergence and resurgence of arboviruses have generated a global
health alert. Among arboviruses, Dengue (DENV), Zika (ZIKV), Yellow Fever (YFV), and …
health alert. Among arboviruses, Dengue (DENV), Zika (ZIKV), Yellow Fever (YFV), and …
The antiviral effect of metformin on zika and dengue virus infection
The Dengue (DENV) and zika (ZIKV) virus infections are currently a public health concern.
At present, there is no treatment or a safe and effective vaccine for these viruses. Hence, the …
At present, there is no treatment or a safe and effective vaccine for these viruses. Hence, the …
Dengue drug discovery: Progress, challenges and outlook
In the context of the only available vaccine (DENGVAXIA) that was marketed in several
countries, but poses higher risks to unexposed individuals, the development of antivirals for …
countries, but poses higher risks to unexposed individuals, the development of antivirals for …
Glycolysis is reduced in dengue virus 2 infected liver cells
C Chumchanchira, S Ramphan, W Sornjai… - Scientific Reports, 2024 - nature.com
Infections with dengue virus (DENV) remain a worldwide public health problem. A number of
bona fide cellular targets of DENV have been identified including liver cells. Despite the …
bona fide cellular targets of DENV have been identified including liver cells. Despite the …
[HTML][HTML] Mosquito-borne flaviviruses and current therapeutic advances
X Qian, Z Qi - Viruses, 2022 - mdpi.com
Mosquito-borne flavivirus infections affect approximately 400 million people worldwide each
year and are global threats to public health. The common diseases caused by such …
year and are global threats to public health. The common diseases caused by such …
Anti-flavivirus properties of lipid-lowering drugs
Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human
pathogens, an effective vaccine or antiviral treatment against them is not available. Hence …
pathogens, an effective vaccine or antiviral treatment against them is not available. Hence …
Protection by metformin against severe Covid-19: An in-depth mechanistic analysis
Since the outbreak of Covid-19, several observational studies on diabetes and Covid-19
have reported a favourable association between metformin and Covid-19-related outcomes …
have reported a favourable association between metformin and Covid-19-related outcomes …
Viral infection and host immune response in diabetes
Diabetes, a chronic metabolic disorder disrupting blood sugar regulation, has emerged as a
prominent silent pandemic. Uncontrolled diabetes predisposes an individual to develop fatal …
prominent silent pandemic. Uncontrolled diabetes predisposes an individual to develop fatal …