Nitric oxide (NO) has complex and diverse functions in physiological and pathophysiological
phenomena. The mechanisms of many events induced by NO are now well defined, so that …

The encephalomyocarditis virus (EMCV) is a small non-enveloped single-strand RNA virus,
the causative agent of not only myocarditis and encephalitis, but also neurological diseases …

Type 1 diabetes results from the destruction of pancreatic beta cells. Genetic factors are
believed to be a major component for the development of type 1diabetes, but the …

During the last decades, the incidence of type 1 diabetes (T1D) has increased significantly,
reaching percentages of 3% annually worldwide. This increase suggests that besides …

Oxygen radicals and nitric oxide (NO) are generated in excess in a diverse array of microbial
infections. Emerging concepts in free radical biology are now shedding light on the …

Human gastric cancer (GC) is characterized by a high incidence and mortality rate, largely
because it is normally not identified until a relatively advanced stage owing to a lack of early …

SUMMARY Melatonin (N‐acetyl‐5‐methoxytryptamine) is a multifunctional signaling
molecule that has a variety of important functions. Numerous clinical trials have examined …

Type I (insulin-dependent) diabetes mellitus results from the progressive loss of pancreatic
beta cells. Environmental factors are believed to play an important part in the development …

Melatonin, a versatile molecule, is synthesized by the pineal gland but also by other organs,
including gastrointestinal tract, retina, thymus, bone marrow, and by leukocytes. Besides …

Vaccinia virus (VV) triggers a mitogenic signal at an early stage of infection. VV-induced
proto-oncogene c-fos mRNA with kinetics paralleling that stimulated by serum. The VV …