Activity‐based sensing: a synthetic methods approach for selective molecular imaging and beyond

KJ Bruemmer, SWM Crossley… - Angewandte Chemie …, 2020 - Wiley Online Library
Emerging from the origins of supramolecular chemistry and the development of selective
chemical receptors that rely on lock‐and‐key binding, activity‐based sensing (ABS)—which …

Molecular fluorescent probes for monitoring pH changes in living cells

R Wang, C Yu, F Yu, L Chen - TrAC Trends in Analytical Chemistry, 2010 - Elsevier
The availability of synthetic fluorescent probes and the development of powerful new
approaches to microscopy have made fluorescence microscopy an essential tool for …

Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain

S Genoud, BR Roberts, AP Gunn, GM Halliday… - Metallomics, 2017 - academic.oup.com
Elevated iron and decreased copper levels are cardinal features of the degenerating
substantia nigra pars compacta in the Parkinson's disease brain. Both of these redox-active …

Both Visual and Fluorescent Sensor for Zn2+ Based on Quinoline Platform

X Zhou, B Yu, Y Guo, X Tang, H Zhang… - Inorganic …, 2010 - ACS Publications
A fluorescent Zn2+ sensor 2-(hydroxymethyl)-4-methyl-6-((quinolinyl-8-imino) methyl)
phenol (HMQP) based on the 8-aminoquinoline platform has been synthesized. This sensor …

Phosphine quenching of cyanine dyes as a versatile tool for fluorescence microscopy

JC Vaughan, GT Dempsey, E Sun… - Journal of the American …, 2013 - ACS Publications
We report that the cyanine dye Cy5 and several of its structural relatives are reversibly
quenched by the phosphine tris (2-carboxyethyl) phosphine (TCEP). Using Cy5 as a model …

Nanoscale metal–organic frameworks as highly sensitive luminescent sensors for Fe 2+ in aqueous solution and living cells

Y Lu, B Yan, JL Liu - Chemical Communications, 2014 - pubs.rsc.org
We report the exploration of fluorescent nanoscale metal–organic frameworks (nMOF-253s)
for highly selective and sensitive detection of Fe2+ ions in aqueous solution. Moreover …

Upconversion nanoparticles for sensitive and in-depth detection of Cu 2+ ions

C Li, J Liu, S Alonso, F Li, Y Zhang - Nanoscale, 2012 - pubs.rsc.org
Detection of Cu2+ ions and study of their subcellular distribution in physiological processes
are of considerable significance because of their potential environmental and biological …

Highly selective excited state intramolecular proton transfer (ESIPT)-based superoxide probing

DP Murale, H Kim, WS Choi, DG Churchill - Organic Letters, 2013 - ACS Publications
Highly Selective Excited State Intramolecular Proton Transfer (ESIPT)-Based Superoxide
Probing | Organic Letters Recently Viewedclose modal ACS ACS Publications C&EN CAS Find …

Indicator displacement assays inside live cells

A Norouzy, Z Azizi, WM Nau - … Chemie International Edition, 2015 - Wiley Online Library
Abstract The macrocycle p‐sulfonatocalix [4] arene (CX4) and the fluorescent dye lucigenin
(LCG) form a stable host–guest complex, in which the dye fluorescence is quenched …

An artificial tongue fluorescent sensor array for identification and quantitation of various heavy metal ions

W Xu, C Ren, CL Teoh, J Peng, SH Gadre… - Analytical …, 2014 - ACS Publications
Herein, a small-molecule fluorescent sensor array for rapid identification of seven heavy
metal ions was designed and synthesized, with its sensing mechanism mimicking that of a …