Ever increasing environmental presence of cadmium as a consequence of industrial
activities is considered a health hazard and is closely linked to deteriorating global health …

Eukaryotes must balance the metabolic and cell death actions of mitochondria via control of
gene expression and cell fate by chromatin, thereby functionally binding the metabolome …

Discontinuous transcription is evolutionarily conserved and a fundamental feature of gene
regulation; yet, the exact mechanisms underlying transcriptional bursting are unresolved …

Three-dimensional (3D) chromatin organization plays a key role in regulating mammalian
genome function; however, many of its physical features at the single-cell level remain …

The nucleus is highly organized, such that factors involved in the transcription and
processing of distinct classes of RNA are confined within specific nuclear bodies,. One …

In mammalian interphase nuclei, more than one thousand large genomic regions are
positioned at the nuclear lamina (NL). These lamina‐associated domains (LAD s) are …

Mutations in A-type nuclear lamins cause dilated cardiomyopathy, which is postulated to
result from dysregulated gene expression due to changes in chromatin organization into …

The human genome is extensively folded into 3-dimensional organization. However, the
detailed 3D chromatin folding structures have not been fully visualized due to the lack of …

Understanding how the packaging of chromatin in the nucleus is regulated and organized to
guide complex cellular and developmental programmes, as well as responses to …

Three-dimensional (3D) chromatin organisation plays a key role in regulating genome
function in higher eukaryotes. Despite recognition that the genome partitions into~ 1Mb …