Establishing neural crest identity: a gene regulatory recipe

M Simões-Costa, ME Bronner - Development, 2015‏ - journals.biologists.com
The neural crest is a stem/progenitor cell population that contributes to a wide variety of
derivatives, including sensory and autonomic ganglia, cartilage and bone of the face and …

Network motifs: theory and experimental approaches

U Alon - Nature Reviews Genetics, 2007‏ - nature.com
Transcription regulation networks control the expression of genes. The transcription
networks of well-studied microorganisms appear to be made up of a small set of recurring …

[کتاب][B] An introduction to systems biology: design principles of biological circuits

U Alon - 2019‏ - api.taylorfrancis.com
Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

Scale-free networks in cell biology

R Albert - Journal of cell science, 2005‏ - journals.biologists.com
A cell's behavior is a consequence of the complex interactions between its numerous
constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling …

Gene regulatory networks and the evolution of animal body plans

EH Davidson, DH Erwin - Science, 2006‏ - science.org
Development of the animal body plan is controlled by large gene regulatory networks
(GRNs), and hence evolution of body plans must depend upon change in the architecture of …

The model organism as a system: integrating'omics' data sets

AR Joyce, BØ Palsson - Nature reviews Molecular cell biology, 2006‏ - nature.com
Various technologies can be used to produce genome-scale, or'omics', data sets that
provide systems-level measurements for virtually all types of cellular components in a model …

Orchestration of floral initiation by APETALA1

K Kaufmann, F Wellmer, JM Muiño, T Ferrier, SE Wuest… - science, 2010‏ - science.org
The MADS-domain transcription factor APETALA1 (AP1) is a key regulator of Arabidopsis
flower development. To understand the molecular mechanisms underlying AP1 function, we …

BoolNet—an R package for generation, reconstruction and analysis of Boolean networks

C Müssel, M Hopfensitz, HA Kestler - Bioinformatics, 2010‏ - academic.oup.com
Motivation: As the study of information processing in living cells moves from individual
pathways to complex regulatory networks, mathematical models and simulation become …

A genomic regulatory element that directs assembly and function of immune-specific AP-1–IRF complexes

E Glasmacher, S Agrawal, AB Chang, TL Murphy… - Science, 2012‏ - science.org
Interferon regulatory factor 4 (IRF4) and IRF8 regulate B, T, macrophage, and dendritic cell
differentiation. They are recruited to cis-regulatory Ets-IRF composite elements by PU. 1 or …

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis

SN Sansom, DS Griffiths, A Faedo, DJ Kleinjan… - PLoS …, 2009‏ - journals.plos.org
Neural stem cell self-renewal, neurogenesis, and cell fate determination are processes that
control the generation of specific classes of neurons at the correct place and time. The …