Although levothyroxine is one of the most prescribed medications in the world, its
bioavailability has been reported to be impaired by many factors, including interfering drugs …

Preterm newborns are forced to adapt to harsh extrauterine conditions and endure
numerous adversities despite their incomplete growth and maturity. The inadequate thyroid …

Context In 2005, a nationwide program of iodine prophylaxis on a voluntary basis was
implemented in Italy by law. However, recent data on iodine status are lacking. Objective …

Congenital hypothyroidism (CH) is the most common preventable cause of intellectual
impairment or failure to thrive by early identification and treatment. In Japan, newborn …

Background: Cytomegalovirus (CMV) is the most common agent of congenital infection in
humans. It is a main cause of neurodevelopmental delay and sensorineural hearing loss in …

Euthyroidism is of profound importance for lifetime health. However, the early diagnosis or
therapeutics of thyroid developmental defects has not been established, mainly due to …

Thyroid hormone (TH) is indispensable for brain development in utero and during the first 2–
3 years of life, and the negative effects of TH deficiency on brain development are …

Congenital hypothyroidism diagnosed by TSH assessment in bloodspot screening may be
overlooked in preterm newborns due to immaturity of the hypothalamus-pituitary-thyroid axis …

Objective To evaluate clinical characteristics of patients with central congenital
hypothyroidism (CH), detected in the Dutch neonatal screening program. This included …

Background Congenital hypothyroidism (CH) is an neonatal endocrine disorder. Traditional
newborn screening is the mainstream method of CH screening, so as to ensure the early …