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Structure and function of the notochord: an essential organ for chordate development
DL Stemple - 2005 - journals.biologists.com
The notochord is the defining structure of the chordates, and has essential roles in
vertebrate development. It serves as a source of midline signals that pattern surrounding …
vertebrate development. It serves as a source of midline signals that pattern surrounding …
The notochord: structure and functions
The notochord is an embryonic midline structure common to all members of the phylum
Chordata, providing both mechanical and signaling cues to the develo** embryo. In …
Chordata, providing both mechanical and signaling cues to the develo** embryo. In …
Targeted degradation of transcription factors by TRAFTACs: transcription factor targeting chimeras
Many diseases, including cancer, stem from aberrant activation or overexpression of
oncoproteins that are associated with multiple signaling pathways. Although proteins with …
oncoproteins that are associated with multiple signaling pathways. Although proteins with …
A genetic screen for mutations affecting embryogenesis in zebrafish
Systematic genome-wide mutagenesis screens for embryonic phenotypes have been
instrumental in the understanding of invertebrate and plant development. Here, we report …
instrumental in the understanding of invertebrate and plant development. Here, we report …
[کتاب][B] Zebrafish
C Nusslein-Volhard, R Dahm - 2002 - books.google.com
The zebrafish has become one of the most important model organisms to study biologial
processes in vivo. As a vertebrate that has many of the strengths of invertebrate model …
processes in vivo. As a vertebrate that has many of the strengths of invertebrate model …
Mutations affecting the development of the embryonic zebrafish brain
In a large scale mutagenesis screen for embryonic mutants in zebrafish, we have identified
63 mutations in 24 loci affecting the morphogenesis of the zebrafish brain. The expression of …
63 mutations in 24 loci affecting the morphogenesis of the zebrafish brain. The expression of …
Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis
The notochord plays critical structural and signaling roles during vertebrate development. At
the center of the vertebrate notochord is a large fluid-filled organelle, the notochord vacuole …
the center of the vertebrate notochord is a large fluid-filled organelle, the notochord vacuole …
Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish
One of the major challenges of developmental biology is understanding the inductive and
morphogenetic processes that shape the vertebrate embryo. In a large-scale genetic screen …
morphogenetic processes that shape the vertebrate embryo. In a large-scale genetic screen …
Mutations affecting craniofacial development in zebrafish
In a large-scale screen for mutations affecting embryogenesis in zebrafish, we identified 48
mutations in 34 genetic loci specifically affecting craniofacial development. Mutants were …
mutations in 34 genetic loci specifically affecting craniofacial development. Mutants were …
BMP-binding modules in chordin: a model for signalling regulation in the extracellular space
ABSTRACT A number of genetic and molecular studies have implicated Chordin in the
regulation of dorsoventral patterning during gastrulation. Chordin, a BMP antagonist of 120 …
regulation of dorsoventral patterning during gastrulation. Chordin, a BMP antagonist of 120 …