Small interfering RNAs (siRNAs) technology has emerged as a promising potential
treatment for viral, genetic diseases and cancers. Despite the powerful therapeutic potential …

Over the past few decades, si RNA and mi RNA have attracted a great deal of attention from
researchers and clinicians. These molecules have been extensively studied from the …

Exosomes, the smallest subgroup of extracellular vesicles, have been recognized as
extracellular organelles that contain genetic and proteomic information for long distance …

MicroRNAs (miRNAs) are small noncoding RNAs that function at the posttranscriptional
level in the cellular regulation process. miRNA expression exerts vital effects on cell growth …

Hydroxyapatite, the main inorganic material in natural bone, has been used widely for
orthopaedic applications. Due to size effects and surface phenomena at the nanoscale …

Nanotechnology is an evolving scientific field that has allowed the manufacturing of
materials with novel physicochemical and biological properties, offering a wide spectrum of …

Due to the absence of safe and effective carriers for in vivo delivery, the applications of small
interference RNA (siRNA) in clinic for therapeutic purposes have been limited. In this study …

Breast cancer is the most frequently diagnosed malignancy in American women. While
significant progress has been made in the development of modern diagnostic tools and …

KRAS mutations are a major cause of drug resistance to molecular-targeted therapies.
Aberrant epidermal growth factor receptor (EGFR) signaling may cause dysregulation of …

Nanocarrier delivery systems have been widely studied to carry unique or dual chemical
drugs. The major challenge of chemotherapies is to overcome the multidrug-resistance …