In the past two decades, record-breaking heatwaves have caused an increasing number of
heat-related deaths, including heatstroke, globally. Heatstroke is a heat illness characterized …

1.1. Background During exercise and with exposure to hot climatic conditions, there is
tendency for the human body to store heat and for body temperatures to rise. Changes in …

New Findings What is the topic of this review? This review outlines the history of research on
epigenetic adaptations to heat exposure. The perspective taken is that adaptations reflect …

New Findings What is the topic of this review? Whether there are sex differences in
exertional heat stroke. What advances does it highlight? This review utilizes a translational …

New Findings What is the topic of this review? The status and potential role of novel
biological markers (biomarkers) that can help identify the patients at risk of organ injury or …

Key points Exposure to exertional heat stroke (EHS) has been linked to increased long‐term
decrements of health. Epigenetic reprogramming is involved in the response to heat …

Female mice have a greater capacity for exercising in the heat than male mice, reaching
greater power output and longer times of heat exposure before succumbing to exertional …

Exposure to early life adversity is linked to detrimental fitness outcomes across taxa. Owing
to the challenges of collecting longitudinal data, direct evidence for long-term fitness effects …

Acute high-intensity exercise can affect cardiac health by altering substance metabolism.
However, few metabolomics-based studies provide data on the effect of exercise along with …

Background Liver damage is one of the most common complications in humans and animals
after heat stress (HS). Sheng Mai San (SMS), a traditional Chinese medicine prescription …