Propofol is an intravenous hypnotic drug that is used for induction and maintenance of
sedation and general anaesthesia. It exerts its effects through potentiation of the inhibitory …

Propofol, a short-acting intravenous anaesthetic agent has gained wide acceptance since its
introduction in the late 80s, not only in operating rooms but also in other departments, due to …

Children exposed to early parental loss from death or separation carry a greater risk for
develo** future psychiatric illnesses, such as major depression and anxiety. Monkeys …

Close to 19% of the world population suffers from anxiety. Current medications for this
chronic mental disorder have improved treatment over the last half century or more, but the …

Affective and anxiety disorders are widely distributed disorders with severe social and
economic effects. Evidence is emphatic that effective treatment helps to restore function and …

Nitric oxide synthase (NOS) positive neurons are located in most brain areas related to
defensive reactions, including the dorsolateral periaqueductal grey (dlPAG). NOS inhibitors …

The effects of microinjection of the nitric oxide (NO) precursor l-arginine (l-Arg), the NO
synthase (NOS) inhibitors N-methyl-l-arginine (l-NAME) and 7-nitroindazole (7-NI), and the …

The action of the novel nitric oxide synthase (NOS) inhibitor 7-nitroindazole (7-NI) was
studied in different exploratory models of anxiety. In the rat plus-maze test, 7-NI potently …

The present review paper describes results indicating the influence of nitric oxide (NO) on
motor control. Our last studies showed that systemic injections of low doses of inhibitors of …

Stressful life events contribute to the development of many neuropsychiatric disorders
including depression and anxiety. Animal studies based on the relationship of stress and …