In recent years, there has been a frequent occurrence of large-scale pests and diseases,
leading to a dramatic increase in the application of pesticides. This practice presents a …

There are many challenges that must be overcome before in silico toxicity predictions are
ripe for regulatory decision-making. Today, mandates in the United States of America and …

Background In silico methods for toxicity prediction have increased significantly in recent
years due to the 3Rs principle. This also applies to predicting reproductive toxicology, which …

The definition, characterisation and assessment of the similarity between target and source
molecules are cornerstones of the acceptance of a read-across prediction to fill a data gap …

In dietary risk assessment, residues of pesticidal ingredients or their metabolites need to be
evaluated for their genotoxic potential. The European Food Safety Authority recommend a …

In dietary risk assessment of plant protection products, residues of active ingredients and
their metabolites need to be evaluated for their genotoxic potential. The European Food …

This study focuses on characterizing the forced degradation products of antidiabetic drugs
glimepiride (GMD) and glyburide (GBD), with previously unexplored genotoxicity. Drugs …

Establishing the safety of impurities in drug substances or products is crucial. The
assessment of genotoxicity for these impurities and determining the acceptable limits pose …

In dietary risk assessment of plant protection products, residues of active ingredients and
their metabolites need to be evaluated for their genotoxic potential. The European Food …

We are concerned with computer simulations of a ring of 20 coupled CSTRs with glycolytic
oscillatory reaction. Each CSTR represents an artificial cell, and the ring can be regarded as …