Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications
In high intensity focused ultrasound (HIFU) therapy, an ultrasound beam is focused within
the body to locally affect the targeted site without damaging intervening tissues. The most …
the body to locally affect the targeted site without damaging intervening tissues. The most …
The histotripsy spectrum: differences and similarities in techniques and instrumentation
Since its inception about two decades ago, histotripsy–a non-thermal mechanical tissue
ablation technique–has evolved into a spectrum of methods, each with distinct potentiating …
ablation technique–has evolved into a spectrum of methods, each with distinct potentiating …
Effects of ultrasound frequency and tissue stiffness on the histotripsy intrinsic threshold for cavitation
Histotripsy is an ultrasound ablation method that depends on the initiation of a cavitation
bubble cloud to fractionate soft tissue. Previous work has indicated that a cavitation cloud …
bubble cloud to fractionate soft tissue. Previous work has indicated that a cavitation cloud …
Effects of tissue stiffness, ultrasound frequency, and pressure on histotripsy-induced cavitation bubble behavior
E Vlaisavljevich, KW Lin, MT Warnez… - Physics in Medicine …, 2015 - iopscience.iop.org
Histotripsy is an ultrasound ablation method that controls cavitation to fractionate soft tissue.
In order to effectively fractionate tissue, histotripsy requires cavitation bubbles to rapidly …
In order to effectively fractionate tissue, histotripsy requires cavitation bubbles to rapidly …
Modeling tissue-selective cavitation damage
L Mancia, E Vlaisavljevich, N Yousefi… - Physics in Medicine …, 2019 - iopscience.iop.org
The destructive growth and collapse of cavitation bubbles are used for therapeutic purposes
in focused ultrasound procedures and can contribute to tissue damage in traumatic injuries …
in focused ultrasound procedures and can contribute to tissue damage in traumatic injuries …
Aberration correction in abdominal histotripsy
E Yeats, TL Hall - International Journal of Hyperthermia, 2023 - Taylor & Francis
In transabdominal histotripsy, ultrasound pulses are focused into the body to noninvasively
destroy soft tissues via cavitation. However, the ability to focus is limited by phase …
destroy soft tissues via cavitation. However, the ability to focus is limited by phase …
Effects of frequency on bubble-cloud behavior and ablation efficiency in intrinsic threshold histotripsy
Objective. Histotripsy is a non-thermal focused ultrasound ablation method that destroys
tissue through the generation of a cavitation bubble cloud. Previous work studying intrinsic …
tissue through the generation of a cavitation bubble cloud. Previous work studying intrinsic …
[HTML][HTML] Endoscopic coregistered ultrasound imaging and precision histotripsy: Initial in vivo evaluation
G LandryThomas, G MallayMatthew… - BME …, 2022 - spj.science.org
Objective. Initial performance evaluation of a system for simultaneous high-resolution
ultrasound imaging and focused mechanical submillimeter histotripsy ablation in rat brains …
ultrasound imaging and focused mechanical submillimeter histotripsy ablation in rat brains …
Targeted lesion generation through the skull without aberration correction using histotripsy
This study demonstrates the ability of histotripsy to generate targeted lesions through the
skullcap without using aberration correction. Histotripsy therapy was delivered using a 500 …
skullcap without using aberration correction. Histotripsy therapy was delivered using a 500 …
Effects of temperature on the histotripsy intrinsic threshold for cavitation
Histotripsy is an ultrasound ablation method that depends on the initiation of a dense
cavitation bubble cloud to fractionate soft tissue. Previous work has demonstrated that a …
cavitation bubble cloud to fractionate soft tissue. Previous work has demonstrated that a …