[HTML][HTML] Tumor spheroid elasticity estimation using mechano-microscopy combined with a conditional generative adversarial network

KY Foo, B Shaddy, J Murgoitio-Esandi… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objectives Techniques for imaging the mechanical properties of
cells are needed to study how cell mechanics influence cell function and disease …

Conditional score-based diffusion models for solving inverse elasticity problems

A Dasgupta, H Ramaswamy, J Murgoitio-Esandi… - Computer Methods in …, 2025 - Elsevier
We propose a framework to perform Bayesian inference using conditional score-based
diffusion models to solve a class of inverse problems in mechanics involving the inference of …

Design and characterization of an optical phantom for mesoscopic multimodal fluorescence lifetime imaging and optical coherence elastography

L Chavez, S Gao, V Pandey, N Yuan… - Biomedical Optics …, 2025 - opg.optica.org
We developed a novel methodology for manufacturing multimodal, tissue-mimicking
phantoms that exhibit both molecular and biomechanical contrast. This methodology …

Mechanical evolution of metastatic cancer cells in three-dimensional microenvironment

K Hilai, D Grubich, M Akrawi, H Zhu, R Zaghloul… - …, 2024 - pmc.ncbi.nlm.nih.gov
Cellular biomechanics plays critical roles in cancer metastasis and tumor progression.
Existing studies on cancer cell biomechanics are mostly conducted in flat 2D conditions …

Biochemical state in tissue can be detected through ultrasound signal

K Ito, Y Iijima, T Misumi, G Hayase, K Tamura… - bioRxiv, 2024 - biorxiv.org
Three-dimensional (3D) cell cultures, such as spheroids, are indispensable models for
investigating cellular behaviors and responses under conditions that closely resemble in …