Despite the success of antiretroviral therapy (ART) for people living with HIV, lifelong
treatment is required and there is no cure. HIV can integrate in the host genome and persist …

Human papillomavirus (HPV), a common sexually transmitted virus infecting mucosal or
cutaneous stratified epithelia, is implicated in the rising of associated cancers worldwide …

The persistence of latent reservoir of the human immunodeficiency virus (HIV) is currently
the major challenge in curing HIV infection. After HIV infects the human body, the latent HIV …

Today HIV infection cannot be cured due to the presence of a reservoir of latently infected
cells inducing a viral rebound upon treatment interruption. Hence, the latent reservoir is …

9 years since the report of a cure for HIV after CC chemokine receptor type 5 Δ32 stem cell
transplantation, no other case of HIV cure has been reported, despite much research …

Abstract 35 years since identification of HIV as the causative agent of AIDS, and 35 million
deaths associated with this disease, significant effort is now directed towards the …

The HIV latent reservoir represents the major challenge to cure development. Residing in
resting CD4+ T cells and myeloid cells at multiple locations in the body, including sanctuary …

Early gene therapy studies held great promise for the cure of heritable diseases, but the
occurrence of various genotoxic events led to a pause in clinical trials and a more guarded …

Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a respiratory
virus that causes COVID-19 disease, with an estimated global mortality of approximately 2 …

It has been over a decade since the first observation that small non-coding RNAs can
functionally modulate epigenetic states in human cells to achieve functional transcriptional …