Protein glycosylation is an essential co-and post-translational modification of secretory and
membrane proteins in all eukaryotes. The initial steps of N-glycosylation and N-glycan …

Galactose is an essential carbohydrate for cellular metabolism, as it contributes to energy
production and storage in several human tissues while also being a precursor for …

SLC39A8 is a membrane transporter responsible for manganese uptake into the cell. Via
whole-exome sequencing, we studied a child that presented with cranial asymmetry, severe …

▪ Abstract Researchers have long predicted that complex carbohydrates on cell surfaces
would play important roles in developmental processes because of the observation that …

Inflammation and cancer metastasis are associated with extravasation of leukocytes or
tumor cells from blood into tissue. Such movement is believed to follow a coordinated and …

A high‐density coding system is essential to allow cells to communicate efficiently and
swiftly through complex surface interactions. All the structural requirements for forming a …

Leukocyte recruitment encompasses cell adhesion and activation steps that enable
circulating leukocytes to roll, arrest, and firmly adhere on the endothelial surface before they …

Intracellular post-translational modifications such as phosphorylation and ubiquitylation
have been well studied for their roles in regulating diverse signalling pathways, but we are …

The tick microbiota is a highly complex ensemble of interacting microorganisms. Keystone
taxa, with a central role in the microbial networks, support the stability and fitness of the …

Leukocyte rolling is an important step for the successful recruitment of leukocytes into tissue
and occurs predominantly in inflamed microvessels and in high endothelial venules of …