Timing of lifespan influences on brain and cognition

KB Walhovd, M Lövden, AM Fjell - Trends in cognitive sciences, 2023 - cell.com
Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …

Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders

C Mu, X Dang, XJ Luo - Nature human behaviour, 2024 - nature.com
Dysfunction of brain resting-state functional networks has been widely reported in
psychiatric disorders. However, the causal relationships between brain resting-state …

Towards interpretable imaging genomics analysis: methodological developments and applications

X Cen, W Dong, W Lv, Y Zhao, F Dubee, AFA Mentis… - Information …, 2024 - Elsevier
Identifying the relationship between imaging features and genetic variation (a term coined
“imaging genomics”) offers valuable insight into the pathogenesis of cancer, as well as …

Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study

K Yu, XF Chen, J Guo, S Wang, XT Huang, Y Guo… - BMC medicine, 2023 - Springer
Background Stroke is a major cause of mortality and long-term disability worldwide. Whether
the associations between brain imaging-derived phenotypes (IDPs) and stroke are causal is …

[HTML][HTML] Homotopic functional connectivity disruptions in schizophrenia and their associated gene expression

M Cai, Y Ji, Q Zhao, H Xue, Z Sun, H Wang, Y Zhang… - Neuroimage, 2024 - Elsevier
It has been revealed that abnormal voxel-mirrored homotopic connectivity (VMHC) is
present in patients with schizophrenia, yet there are inconsistencies in the relevant findings …

Dissecting the causal association between social or physical inactivity and depression: a bidirectional two-sample Mendelian Randomization study

G Zhao, Z Lu, Y Sun, Z Kang, X Feng, Y Liao… - Translational …, 2023 - nature.com
A growing body of research suggests that social or physical activity can affect the risk of
Major depressive disorder (MDD). However, the bidirectional relationship between them …

The genetic relationships between brain structure and schizophrenia

EM Stauffer, RAI Bethlehem, L Dorfschmidt… - Nature …, 2023 - nature.com
Genetic risks for schizophrenia are theoretically mediated by genetic effects on brain
structure but it has been unclear which genes are associated with both schizophrenia and …

Mendelian randomization and transcriptomic analysis reveal an inverse causal relationship between Alzheimer's disease and cancer

Z Dong, M Xu, X Sun, X Wang - Journal of Translational Medicine, 2023 - Springer
Background Alzheimer's disease (AD) and cancer are common age-related diseases, and
epidemiological evidence suggests an inverse relationship between them. However …

Causal relationships between screen use, reading, and brain development in early adolescents

M Li, R Zhao, X Dang, X Xu, R Chen, Y Chen… - Advanced …, 2024 - Wiley Online Library
The rise of new media has greatly changed the lifestyles, leading to increased time on these
platforms and less time spent reading. This shift has particularly profound impacts on early …

Causal relationships between migraine and microstructural white matter: a Mendelian randomization study

L Zhao, W Zhao, J Cao, Y Tu - The journal of headache and pain, 2023 - Springer
Background Migraine is a disabling neurological disorder with the pathophysiology yet to be
understood. The microstructural alteration in brain white matter (WM) has been suggested to …