Machine and deep learning meet genome-scale metabolic modeling

G Zampieri, S Vijayakumar, E Yaneske… - PLoS computational …, 2019 - journals.plos.org
Omic data analysis is steadily growing as a driver of basic and applied molecular biology
research. Core to the interpretation of complex and heterogeneous biological phenotypes …

Past, present and future of gene feature selection for breast cancer classification–a survey

CL Chowdhary, N Khare, H Patel… - International …, 2022 - inderscienceonline.com
Computational-based analysis of gene expression to evaluate the genetic pattern provides
better breast cancer prediction. It is a challenge to identify these samples correctly and …

A top-r feature selection algorithm for microarray gene expression data

A Sharma, S Imoto, S Miyano - IEEE/ACM Transactions on …, 2011 - ieeexplore.ieee.org
Most of the conventional feature selection algorithms have a drawback whereby a weakly
ranked gene that could perform well in terms of classification accuracy with an appropriate …

Simulation of open quantum dynamics with bootstrap-based long short-term memory recurrent neural network

K Lin, J Peng, FL Gu, Z Lan - The Journal of Physical Chemistry …, 2021 - ACS Publications
The recurrent neural network with the long short-term memory cell (LSTM-NN) is employed
to simulate the long-time dynamics of open quantum systems. The bootstrap method is …

[HTML][HTML] Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search …

V Elyasigomari, DA Lee, HRC Screen… - Journal of biomedical …, 2017 - Elsevier
For each cancer type, only a few genes are informative. Due to the so-called 'curse of
dimensionality'problem, the gene selection task remains a challenge. To overcome this …

Unique: A framework for uncertainty quantification benchmarking

J Lanini, MTD Huynh, G Scebba… - Journal of chemical …, 2024 - ACS Publications
Machine learning (ML) models have become key in decision-making for many disciplines,
including drug discovery and medicinal chemistry. ML models are generally evaluated prior …

Computer-aided drug design

PV Bharatam - Drug discovery and development: From targets and …, 2021 - Springer
Abstract Computer-Aided Drug Design topic deals with the application of computer
hardware and software to provide solutions at every stage of drug discovery. QSAR methods …

Privacy-preserving outsourced support vector machine design for secure drug discovery

X Liu, RH Deng, KKR Choo… - IEEE Transactions on …, 2018 - ieeexplore.ieee.org
In this paper, we propose a framework for privacy-preserving outsourced drug discovery in
the cloud, which we refer to as POD. Specifically, POD is designed to allow the cloud to …

An introduction to clustering algorithms in big data

R Nair, A Bhagat - … of Information Science and Technology, Fifth …, 2021 - igi-global.com
In big data, clustering is the process through which analysis is performed. Since the data is
big, it is very difficult to perform clustering approach. Big data is mainly termed as petabytes …

Cancer classification using a novel gene selection approach by means of shuffling based on data clustering with optimization

V Elyasigomari, MS Mirjafari, HRC Screen… - Applied Soft …, 2015 - Elsevier
This research presents an innovative method for cancer identification and type classification
using microarray data. The method is based on gene selection with shuffling in association …