Evidences for adult hippocampal neurogenesis in humans

EP Moreno-Jiménez, J Terreros-Roncal… - Journal of …, 2021 - Soc Neuroscience
The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

Early life adversity shapes neural circuit function during sensitive postnatal developmental periods

L Malave, MT van Dijk, C Anacker - Translational psychiatry, 2022 - nature.com
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …

Adult-born dentate granule cells promote hippocampal population sparsity

SB McHugh, V Lopes-dos-Santos, GP Gava… - Nature …, 2022 - nature.com
The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly,
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …

Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories

T Hainmueller, M Bartos - Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

The role of adult hippocampal neurogenesis in brain health and disease

T Toda, SL Parylak, SB Linker, FH Gage - Molecular psychiatry, 2019 - nature.com
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

C Anacker, VM Luna, GS Stevens, A Millette, R Shores… - Nature, 2018 - nature.com
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by
environmental influences, and functionally implicated in behavioural responses to stress …

Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood

C Anacker, R Hen - Nature Reviews Neuroscience, 2017 - nature.com
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Adult neurogenesis in the hippocampus: from stem cells to behavior

JT Gonçalves, ST Schafer, FH Gage - Cell, 2016 - cell.com
The dentate gyrus of the mammalian hippocampus continuously generates new neurons
during adulthood. These adult-born neurons become functionally active and are thought to …

Optogenetics: 10 years of microbial opsins in neuroscience

K Deisseroth - Nature neuroscience, 2015 - nature.com
Over the past 10 years, the development and convergence of microbial opsin engineering,
modular genetic methods for cell-type targeting and optical strategies for guiding light …

Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior

YD Li, YJ Luo, ZK Chen, L Quintanilla, Y Cherasse… - Nature …, 2022 - nature.com
Adult hippocampal neurogenesis plays a critical role in memory and emotion processing,
and this process is dynamically regulated by neural circuit activity. However, it remains …