Zinc as a gatekeeper of immune function
I Wessels, M Maywald, L Rink - Nutrients, 2017 - mdpi.com
After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …
for the function of the immune system. Zinc ions are involved in regulating intracellular …
Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism
A number of studies have reported that zinc plays a substantial role in the development of
metabolic syndrome, taking part in the regulation of cytokine expression, suppressing …
metabolic syndrome, taking part in the regulation of cytokine expression, suppressing …
Dietary and physiological effects of zinc on the immune system
I Wessels, HJ Fischer, L Rink - Annual review of nutrition, 2021 - annualreviews.org
Evidence for the importance of zinc for all immune cells and for mounting an efficient and
balanced immune response to various environmental stressors has been accumulating in …
balanced immune response to various environmental stressors has been accumulating in …
Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets
Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …
key observation is the disruption of cellular homeostasis, often coinciding with disease …
Molecular mechanisms of zinc as a pro-antioxidant mediator: clinical therapeutic implications
AS Prasad, B Bao - Antioxidants, 2019 - mdpi.com
The essentiality of zinc as a trace mineral in human health has been recognized for over five
decades. Zinc deficiency, caused by diet, genetic defects, or diseases, can cause growth …
decades. Zinc deficiency, caused by diet, genetic defects, or diseases, can cause growth …
Protein acetylation in metabolism—metabolites and cofactors
KJ Menzies, H Zhang, E Katsyuba… - Nature Reviews …, 2016 - nature.com
Reversible acetylation was initially described as an epigenetic mechanism regulating DNA
accessibility. Since then, this process has emerged as a controller of histone and nonhistone …
accessibility. Since then, this process has emerged as a controller of histone and nonhistone …
Nutrition in patients with type 2 diabetes: present knowledge and remaining challenges
Unhealthy behaviours, including diet and physical activity, coupled with genetic
predisposition, drive type 2 diabetes (T2D) occurrence and severity; the present review aims …
predisposition, drive type 2 diabetes (T2D) occurrence and severity; the present review aims …
The role of zinc and copper in insulin resistance and diabetes mellitus
The prevalence of Type 2 Diabetes Mellitus (T2DM) is internationally ever-growing.
Therefore, prevention, diagnostics, and control of insulin resistance and T2DM are of …
Therefore, prevention, diagnostics, and control of insulin resistance and T2DM are of …
[HTML][HTML] Zinc supplementation improves glycemic control for diabetes prevention and management: a systematic review and meta-analysis of randomized controlled …
X Wang, W Wu, W Zheng, X Fang, L Chen… - The American journal of …, 2019 - Elsevier
Background Although many studies have shown that low zinc status is associated with
diabetes, the putative effects of zinc supplementation on glycemic control are inconclusive …
diabetes, the putative effects of zinc supplementation on glycemic control are inconclusive …
Associations between zinc deficiency and metabolic abnormalities in patients with chronic liver disease
T Himoto, T Masaki - Nutrients, 2018 - mdpi.com
Zinc (Zn) is an essential trace element which has favorable antioxidant, anti-inflammatory,
and apoptotic effects. The liver mainly plays a crucial role in maintaining systemic Zn …
and apoptotic effects. The liver mainly plays a crucial role in maintaining systemic Zn …