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Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer
A variety of targeted anticancer agents have been successfully introduced into clinical
practice, largely reflecting their ability to inhibit specific molecular alterations that are …
practice, largely reflecting their ability to inhibit specific molecular alterations that are …
Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia
Purpose Cancer-related mortality, a leading cause of death worldwide, is often the result of
metastatic disease recurrence. Anesthetic techniques have varying effects on innate and …
metastatic disease recurrence. Anesthetic techniques have varying effects on innate and …
[HTML][HTML] Influence of perioperative anaesthetic and analgesic interventions on oncological outcomes: a narrative review
Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …
Unfortunately, cancer recurrence following surgery of curative intent is common, and …
Perioperative neurocognitive disorder: state of the preclinical science
The purpose of this white paper is to provide a succinct summary of the different
experimental approaches that have been used in preclinical post-operative cognitive …
experimental approaches that have been used in preclinical post-operative cognitive …
[HTML][HTML] Inhaled anesthetics: environmental role, occupational risk, and clinical use
Inhaled anesthetics have been in clinical use for over 150 years and are still commonly used
in daily practice. The initial view of inhaled anesthetics as indispensable for general …
in daily practice. The initial view of inhaled anesthetics as indispensable for general …
Norepinephrine dysregulates the immune response and compromises host defense during sepsis
RF Stolk, E van der Pasch, F Naumann… - American journal of …, 2020 - atsjournals.org
Rationale: Sepsis is characterized by a dysregulated immune response to infection.
Norepinephrine, the cornerstone vasopressor used in septic shock, may contribute to …
Norepinephrine, the cornerstone vasopressor used in septic shock, may contribute to …
Caffeic acid phenethyl ester suppresses oxidative stress and regulates M1/M2 microglia polarization via Sirt6/Nrf2 pathway to mitigate cognitive impairment in aged …
Postoperative cognitive dysfunction (POCD) is a severe neurological complication after
anesthesia and surgery. However, there is still a lack of effective clinical pharmacotherapy …
anesthesia and surgery. However, there is still a lack of effective clinical pharmacotherapy …
Total intravenous anesthesia versus inhalation anesthesia for breast cancer surgery: A retrospective cohort study.
Background The association between type of anesthesia used and recurrence of cancer
remains controversial. This retrospective cohort study compared the influence of total IV …
remains controversial. This retrospective cohort study compared the influence of total IV …
Anesthesia and long-term oncological outcomes: a systematic review and meta-analysis
BACKGROUND: Whether propofol elicits a survival benefit over volatile anesthetics during
cancer surgery remains inconclusive. The primary aim of this systematic review and meta …
cancer surgery remains inconclusive. The primary aim of this systematic review and meta …
Postoperative cognitive dysfunction in the aged: the collision of neuroinflammaging with perioperative neuroinflammation
The aging population is burgeoning globally and this trend presents great challenges to the
current healthcare system as the growing number of aged individuals receives procedures …
current healthcare system as the growing number of aged individuals receives procedures …