The incorporation of a synthetic, catalytically competent metallocofactor into a protein
scaffold to generate an artificial metalloenzyme (ArM) has been explored since the late …

Hydrogenation is one of the most fundamental transformations in organic synthesis, and its
industrial applications span from fine chemicals to pharmaceuticals synthesis. 1− 3 Direct …

Organofluorine chemistry is an area of tremendous expansion. 1 The field of applications is
impressively wide in scope and has the potential to concern all fields of society. Indeed …

Deactivation leads to loss of catalyst activity or selectivity with increasing reaction time, but
has attracted less academic attention in homogeneous catalysis than is justified by its …

Recent development of conceptually new chiral bifunctional transition metal based catalysts
for asymmetric reductive transformations is described. The chiral bifunctional molecular …

Hydrogen transfer reduction processes are attracting increasing interest from synthetic
chemists in view of their operational simplicity and high selectivity. In this tutorial review the …

Asymmetric hydrogenation of acetophenone with trans-RuH (η1-BH4)[(S)-tolbinap][(S, S)-
dpen](TolBINAP= 2, 2 '-bis (di-4-tolylphosphino)-1, 1 '-binaphthyl; DPEN= 1, 2 …

Recent developments in task specifically functionalized imidazolium salts, which can be
used for specific tasks ranging from catalysts recycling, supports for organic synthesis …

Asymmetric transfer hydrogenation has become a practically useful tool in reduction
chemistry in the last decade or so. This was largely triggered by the seminal work of Noyori …

Ruthenium dimer 6 (readily available in two steps from TsDPEN) is converted directly to
monomeric asymmetric transfer hydrogenation catalyst 3 in situ under the conditions …