Reactive oxygen species in cell signaling
VJ Thannickal, BL Fanburg - American Journal of …, 2000 - journals.physiology.org
Reactive oxygen species (ROS) are generated as by-products of cellular metabolism,
primarily in the mitochondria. When cellular production of ROS overwhelms its antioxidant …
primarily in the mitochondria. When cellular production of ROS overwhelms its antioxidant …
Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells
J Boonstra, JA Post - Gene, 2004 - Elsevier
Cell cycle progression is regulated by a wide variety of external factors, amongst them are
growth factors and extracellular matrix factors. During the last decades evidence has been …
growth factors and extracellular matrix factors. During the last decades evidence has been …
Evolution of catalases from bacteria to humans
Excessive hydrogen peroxide is harmful for almost all cell components, so its rapid and
efficient removal is of essential importance for aerobically living organisms. Conversely …
efficient removal is of essential importance for aerobically living organisms. Conversely …
Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis
CS Sander, H Chang, F Hamm… - International journal …, 2004 - Wiley Online Library
Melanoma and nonmelanoma skin cancers are among the most prevalent cancers in the
human population. Solar ultraviolet radiation is considered a major etiological factor but the …
human population. Solar ultraviolet radiation is considered a major etiological factor but the …
Mitochondrial redox control of matrix metalloproteinases
KK Nelson, JA Melendez - Free Radical Biology and Medicine, 2004 - Elsevier
Reactive oxygen species (ROS) are constantly generated in aerobic organisms during
normal metabolism and in response to both internal and external stimuli. Imbalances in the …
normal metabolism and in response to both internal and external stimuli. Imbalances in the …
Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (−)-epigallocatechin,(−)-epigallocatechin gallate,(+)-catechin, and quercetin to commonly …
There is considerable current interest in the possible beneficial health effects of quercetin,
catechins, epigallocatechins, epigallocatechin gallates, and related phenolic compounds …
catechins, epigallocatechins, epigallocatechin gallates, and related phenolic compounds …
The pathogenesis of pterygium: current concepts and their therapeutic implications
Pterygium is a disease of the ocular surface that is associated with chronic UV exposure and
is characterized by proliferation, inflammatory infiltrates, fibrosis, angiogenesis and …
is characterized by proliferation, inflammatory infiltrates, fibrosis, angiogenesis and …
Role of hydrogen peroxide and oxidative stress in healing responses
M Rojkind, JA Dominguez-Rosales, N Nieto… - Cellular and Molecular …, 2002 - Springer
Oxidative stress is a host defense mechanism whose involvement in maintaining
homeostasis and/or inducing disease has been widely investigated over the past decade …
homeostasis and/or inducing disease has been widely investigated over the past decade …
Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity
K Dittmann, C Mayer, HP Rodemann - Radiotherapy and Oncology, 2005 - Elsevier
BACKGROUND AND PURPOSE: Inhibition of EGFR-function can induce radiosensitization
in tumor cells. Purpose of our investigation was to identify the possible molecular …
in tumor cells. Purpose of our investigation was to identify the possible molecular …
Photooxidation of Amplex Red to resorufin: implications of exposing the Amplex Red assay to light
The Amplex Red assay, a fluorescent assay for the detection of H2O2, relies on the reaction
of H2O2 and colorless, nonfluorescent Amplex Red with a 1: 1 stoichiometry to form colored …
of H2O2 and colorless, nonfluorescent Amplex Red with a 1: 1 stoichiometry to form colored …