Abstract Calcium–calmodulin (CaM)-dependent protein kinase II (CaMKII) is the most
abundant protein in excitatory synapses and is central to synaptic plasticity, learning and …

CaMKII (the multifunctional Ca2+ and calmodulin-dependent protein kinase II) is a highly
validated signal for promoting a variety of common diseases, particularly in the …

The predominant focus in the neurobiological study of memory has been on remembering
(persistence). However, recent studies have considered the neurobiology of forgetting …

Learning and memory are two of the most magical capabilities of our mind. Learning is the
biological process of acquiring new knowledge about the world, and memory is the process …

It has been proposed that memories are encoded by modification of synaptic strengths
through cellular mechanisms such as long-term potentiation (LTP) and long-term depression …

Maneuvering safely through the environment is central to survival of almost all species. The
ability to do this depends on learning and remembering locations. This capacity is encoded …

The analysis of the contributions to synaptic plasticity and memory of cAMP, PKA, CRE,
CREB-1, CREB-2, and CPEB has recruited the efforts of many laboratories all over the …

Synapses connect neurons together to form the circuits of the brain, and their molecular
composition controls innate and learned behavior. We analyzed the molecular and …

The Morris water maze (MWM) is a test of spatial learning for rodents that relies on distal
cues to navigate from start locations around the perimeter of an open swimming arena to …

The synapse is the functional unit of the brain. During the last several decades we have
acquired a great deal of information on its structure, molecular components, and …