Recent advances in microfluidic technology for bioanalysis and diagnostics

SF Berlanda, M Breitfeld, CL Dietsche… - Analytical …, 2020 - ACS Publications
Microfluidics has become a mature technology, providing an excellent toolbox for the
handling and manipulation of fluid samples, suspended cells, and particles. About 30 years …

The phospholipid research center: current research in phospholipids and their use in drug delivery

S Drescher, P van Hoogevest - Pharmaceutics, 2020 - mdpi.com
This review summarizes the research on phospholipids and their use for drug delivery
related to the Phospholipid Research Center Heidelberg (PRC). The focus is on projects that …

Controlled division of cell-sized vesicles by low densities of membrane-bound proteins

J Steinkühler, RL Knorr, Z Zhao, T Bhatia… - Nature …, 2020 - nature.com
The proliferation of life on earth is based on the ability of single cells to divide into two
daughter cells. During cell division, the plasma membrane undergoes a series of …

pH-controlled coacervate–membrane interactions within liposomes

MGF Last, S Deshpande, C Dekker - ACS nano, 2020 - ACS Publications
Membraneless organelles formed by liquid–liquid phase separation are dynamic structures
that are employed by cells to spatiotemporally regulate their interior. Indeed, complex …

Biocatalytic self-assembled synthetic vesicles and coacervates: From single compartment to artificial cells

D Gaur, NC Dubey, BP Tripathi - Advances in Colloid and Interface Science, 2022 - Elsevier
Compartmentalization is an intrinsic feature of living cells that allows spatiotemporal control
over the biochemical pathways expressed in them. Over the years, a library of …

Microfluidic Platforms for Real‐Time In Situ Monitoring of Biomarkers for Cellular Processes

C Lou, H Yang, Y Hou, H Huang, J Qiu… - Advanced …, 2024 - Wiley Online Library
Cellular processes are mechanisms carried out at the cellular level that are aimed at
guaranteeing the stability of the organism they comprise. The investigation of cellular …

Can bottom-up synthetic biology generate advanced drug-delivery systems?

F Lussier, O Staufer, I Platzman, JP Spatz - Trends in Biotechnology, 2021 - cell.com
Creating a magic bullet that can selectively kill cancer cells while sparing nearby healthy
cells remains one of the most ambitious objectives in pharmacology. Nanomedicine, which …

Microfluidics for peptidomics, proteomics, and cell analysis

R Vitorino, S Guedes, JP da Costa, V Kašička - Nanomaterials, 2021 - mdpi.com
Microfluidics is the advanced microtechnology of fluid manipulation in channels with at least
one dimension in the range of 1–100 microns. Microfluidic technology offers a growing …

Advances in giant unilamellar vesicle preparation techniques and applications

KS Nair, H Bajaj - Advances in Colloid and Interface Science, 2023 - Elsevier
Giant unilamellar vesicles (GUVs) are versatile and promising cell-sized bio-membrane
mimetic platforms. Their applications range from understanding and quantifying membrane …

Breaching the barrier: quantifying antibiotic permeability across gram-negative bacterial membranes

J Cama, AM Henney, M Winterhalter - Journal of Molecular Biology, 2019 - Elsevier
The double-membrane cell envelope of Gram-negative bacteria is a sophisticated barrier
that facilitates the uptake of nutrients and protects the organism from toxic compounds. An …