Although numerous studies have investigated modifiable risk factors for mild cognitive
impairment (MCI) among community-dwelling seniors, no meta-analysis has summarized …

Acid-related disorders represent a significant global health burden. Pharmacological
treatment of these conditions has at times been challenged and limited by incomplete …

Background and Objectives Studies on the association between proton pump inhibitor (PPI)
use and dementia report mixed results and do not examine the impact of cumulative PPI …

Numerous observational studies suggest associations between proton pump inhibitors
(PPIs) and dementia, but causal relationships remain uncertain. Using large-scale genome …

Objectives: Evaluate the mechanism of action of H2 receptor blockers. Assess the adverse
drug reactions associated with H2 receptor blocker administration. Identify the indications for …

Despite reliable evidence of adverse drug effects, the substantially increased prescription
rates of proton pump inhibitors (PPIs) remain at a high level. This study analyzed the …

Neuropsychiatric adverse events (AEs) significantly impact the quality of life of patients using
avapritinib. However, the majority of current data comes from pre-marketing, with limited real …

Objective The association between proton pump inhibitor (PPI) and dementia was
controversial. The aim of the current study was to perform an updated pharmacovigilance …

Background Dementia is a global public health challenge. Certain medications, such as
anticholinergics and benzodiazepines, have been linked to an increased dementia risk …

Aims This study aimed to investigate the association between use of proton pump inhibitors
(PPI) and frailty index (FI), and to assess the causality relationship using Mendelian …