This review reports in detail the cellular and molecular mechanisms which regulate the bone
remodeling process in relation to oxidative stress (OS), inflammatory factors, and estrogen …

Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …

The success of regenerative medicine in various clinical applications depends on the
appropriate selection of the source of mesenchymal stem cells (MSCs). Indeed, the source …

Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

Human mesenchymal stem cells (MSCs) have become a hot topic in the development of cell
therapies and bioengineering. All kinds of MSCs are genomic stable and have the self …

The regeneration of bone fractures, resulting from trauma, osteoporosis or tumors, is a major
problem in our super-aging society. Bone regeneration is one of the main topics of concern …

Bone defects resulting from trauma, illness or congenital abnormalities represent a
significant challenge to global health. Conventional treatments such as autographs and …

The field of tissue engineering continues to advance, sometimes in exponential leaps
forward, but also sometimes at a rate that does not fulfill the promise that the field imagined a …

Stem cells are the central element of regenerative medicine (RM). However, in many clinical
applications, the use of scaffolds fabricated with biomaterials is required. In this sense …

Bone defects cause significant socio-economic costs worldwide, while the clinical “gold
standard” of bone repair, the autologous bone graft, has limitations including limited graft …