Neurobehavioural effects of developmental toxicity

P Grandjean, PJ Landrigan - The lancet neurology, 2014 - thelancet.com
Neurodevelopmental disabilities, including autism, attention-deficit hyperactivity disorder,
dyslexia, and other cognitive impairments, affect millions of children worldwide, and some …

An ecotoxicological view on neurotoxicity assessment

JB Legradi, C Di Paolo, MHS Kraak… - Environmental Sciences …, 2018 - Springer
The numbers of potential neurotoxicants in the environment are raising and pose a great risk
for humans and the environment. Currently neurotoxicity assessment is mostly performed to …

The role of behavioral ecotoxicology in environmental protection

AT Ford, M Ågerstrand, BW Brooks, J Allen… - … science & technology, 2021 - ACS Publications
For decades, we have known that chemicals affect human and wildlife behavior. Moreover,
due to recent technological and computational advances, scientists are now increasingly …

[HTML][HTML] Establishment of a human cell-based in vitro battery to assess developmental neurotoxicity hazard of chemicals

J Blum, S Masjosthusmann, K Bartmann, F Bendt… - Chemosphere, 2023 - Elsevier
Developmental neurotoxicity (DNT) is a major safety concern for all chemicals of the human
exposome. However, DNT data from animal studies are available for only a small …

[КНИГА][B] Hayes' principles and methods of toxicology

AW Hayes, T Kobets - 2023 - taylorfrancis.com
Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

What causes autism? Exploring the environmental contribution

PJ Landrigan - Current opinion in pediatrics, 2010 - journals.lww.com
Expanded research is needed into environmental causation of autism. Children today are
surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in …

[HTML][HTML] Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods

A Bal-Price, F Pistollato, M Sachana, SK Bopp… - Toxicology and applied …, 2018 - Elsevier
Currently, the identification of chemicals that have the potential to induce developmental
neurotoxicity (DNT) is based on animal testing. Since at the regulatory level, systematic …

New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project

T Tal, O Myhre, E Fritsche, J Rüegg, K Craenen… - Frontiers in …, 2024 - frontiersin.org
In the European regulatory context, rodent in vivo studies are the predominant source of
neurotoxicity information. Although they form a cornerstone of neurotoxicological …

[КНИГА][B] Analysis of neural data

RE Kass, UT Eden, EN Brown - 2014 - Springer
This book serves as a guide and reference for anyone who wishes to understand analysis of
neural data generated from studies that range from molecules, to circuits, to systems, to …

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

AK Krug, R Kolde, JA Gaspar, E Rempel… - Archives of …, 2013 - Springer
Developmental neurotoxicity (DNT) and many forms of reproductive toxicity (RT) often
manifest themselves in functional deficits that are not necessarily based on cell death, but …