Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

Muscle atrophy in patients with Type 2 Diabetes Mellitus: roles of inflammatory pathways, physical activity and exercise

BD Perry, MK Caldow… - Exercise …, 2016 - pmc.ncbi.nlm.nih.gov
Muscle atrophy is caused by an imbalance in contractile protein synthesis and degradation
which can be triggered by various conditions including Type 2 Diabetes Mellitus (T2DM) …

The effect of exercise training on resting concentrations of peripheral brain-derived neurotrophic factor (BDNF): a meta-analysis

A Dinoff, N Herrmann, W Swardfager, CS Liu… - PloS one, 2016 - journals.plos.org
Background The mechanisms through which physical activity supports healthy brain function
remain to be elucidated. One hypothesis suggests that increased brain-derived neurotrophic …

The effects of physical activity and exercise on brain‐derived neurotrophic factor in healthy humans: A review

T Huang, KT Larsen, M Ried‐Larsen… - … journal of medicine …, 2014 - Wiley Online Library
The purpose of this study was to summarize the effects of physical activity and exercise on
peripheral brain‐derived neurotrophic factor (BDNF) in healthy humans. Experimental and …

Neuroplasticity—exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects

K Knaepen, M Goekint, EM Heyman, R Meeusen - Sports medicine, 2010 - Springer
Exercise is known to induce a cascade of molecular and cellular processes that support
brain plasticity. Brain-derived neurotrophic factor (BDNF) is an essential neurotrophin that is …

Exercise, brain, and cognition across the life span

MW Voss, LS Nagamatsu… - Journal of applied …, 2011 - journals.physiology.org
This is a brief review of current evidence for the relationships between physical activity and
exercise and the brain and cognition throughout the life span in non-pathological …

Influence of resistance exercise on lean body mass in aging adults: a meta-analysis

MD Peterson, A Sen… - Medicine and science in …, 2011 - pmc.ncbi.nlm.nih.gov
Purpose Sarcopenia plays a principal role in the pathogenesis of frailty and functional
impairment that occurs with aging. There are few published accounts which examine the …

[HTML][HTML] Exercise for brain health: an investigation into the underlying mechanisms guided by dose

DF Cabral, J Rice, TP Morris, T Rundek… - …, 2019 - Elsevier
There is a strong link between the practice of regular physical exercise and maintenance of
cognitive brain health. Animal and human studies have shown that exercise exerts positive …

The effects of aerobic exercise intensity and duration on levels of brain-derived neurotrophic factor in healthy men

MT Schmolesky, DL Webb… - Journal of sports science …, 2013 - pmc.ncbi.nlm.nih.gov
This study examined the combined effects of aerobic exercise intensity and duration on
serum brain-derived neurotrophic factor (sBDNF) levels in healthy human adult males aged …

[PDF][PDF] The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies

J Pilc - Journal of physiology and pharmacology, 2010 - academia.edu
It is well documented that physical activity can induce a number of various stimuli which are
able to enhance the strength and endurance performance of muscles. Moreover, regular …