Coptidis Rhizoma: a comprehensive review of its traditional uses, botany, phytochemistry, pharmacology and toxicology

J Wang, L Wang, GH Lou, HR Zeng, J Hu… - Pharmaceutical …, 2019 - Taylor & Francis
Abstract Context: Coptidis rhizome (CR), also known as Huanglian in Chinese, is the
rhizome of Coptis chinensis Franch., C. deltoidea CY Cheng et Hsiao, or C. teeta Wall …

Molecular targets of epigallocatechin—Gallate (EGCG): A special focus on signal transduction and cancer

A Negri, V Naponelli, F Rizzi, S Bettuzzi - Nutrients, 2018 - mdpi.com
Green tea is a beverage that is widely consumed worldwide and is believed to exert effects
on different diseases, including cancer. The major components of green tea are catechins, a …

Coptisine from Coptis chinensis exerts diverse beneficial properties: A concise review

J Wu, Y Luo, D Deng, S Su, S Li, L **ang… - Journal of cellular …, 2019 - Wiley Online Library
Coptisine is a natural small‐molecular compound extracted from Coptis chinensis (CC) with
a history of using for thousands of years. This work aimed at summarizing coptisine's activity …

Current Advances in Coptidis Rhizoma for Gastrointestinal and Other Cancers

L He, Z Zhong, M Chen, Q Liang, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Cancer is a serious disease with an increasing number of reported cases and high mortality
worldwide. Gastrointestinal cancer defines a group of cancers in the digestive system, eg …

New insights into mechanisms traditional Chinese medicine for allergic rhinitis by regulating inflammatory and oxidative stress pathways

Z Qin, L **e, W Li, C Wang, Y Li - Journal of asthma and allergy, 2024 - Taylor & Francis
Allergy rhinitis (AR) is becoming more common and has serious medical and societal
consequences. Sneezing, paroxysmal nasal blockage, nasal itching, mucosal edema …

[HTML][HTML] Isoquinoline Alkaloids from Coptis chinensis Franch: Focus on Coptisine as a Potential Therapeutic Candidate against Gastric Cancer Cells

S Nakonieczna, A Grabarska, K Gawel… - International Journal of …, 2022 - mdpi.com
Gastric cancer (GC) has high incidence rates and constitutes a common cause of cancer
mortality. Despite advances in treatment, GC remains a challenge in cancer therapy which is …

Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives

L Zhou, F Tan, X Zhang, Y Li, W Yin - IUBMB life, 2024 - Wiley Online Library
Ginsenosides are the primary component discernible from ginseng, including Rb1, Rb2, Rd,
Rg1, Rg2, and compound K, and so forth. They have been shown to have multiple …

Coptisine, the Characteristic Constituent from Coptis chinensis, Exhibits Significant Therapeutic Potential in Treating Cancers, Metabolic and Inflammatory Diseases

Q Lu, Y Tang, S Luo, Q Gong, C Li - The American Journal of …, 2023 - World Scientific
Naturally derived alkaloids belong to a class of quite significant organic compounds.
Coptisine, a benzyl tetrahydroisoquinoline alkaloid, is one of the major bioactive …

The potential application of Chinese medicine in liver diseases: a new opportunity

K Fu, C Wang, C Ma, H Zhou, Y Li - Frontiers in Pharmacology, 2021 - frontiersin.org
Liver diseases have been a common challenge for people all over the world, which
threatens the quality of life and safety of hundreds of millions of patients. China is a major …

The pathogenesis of liver cancer and the therapeutic potential of bioactive substances

S Gao, X Jiang, L Wang, S Jiang, H Luo… - Frontiers in …, 2022 - frontiersin.org
Liver cancer is the third most common cause of cancer-related deaths in the world and has
become an urgent problem for global public health. Bioactive substances are widely used …