Neutrophil extracellular traps expelled from suicidal neutrophils comprise a complex
structure of nuclear chromatin and proteins of nuclear, granular, and cytosolic origin. These …

Psoriasis is a common inflammatory skin disease characterized by the appearance of red
scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration …

Atherosclerosis is considered a chronic inflammatory disease of the arterial wall. Recently,
compelling evidence has arisen for the role of monocytes and neutrophils and a particular …

Neutrophils and neutrophil-like cells are the major pathogen-fighting immune cells in
organisms ranging from slime molds to mammals. Central to their function is their ability to …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Background—Inflammation and activation of immune cells are key mechanisms in the
development of atherosclerosis. Previous data indicate important roles for monocytes and T …

Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in
the pathophysiology of atherosclerosis has been largely denied. However, over the past …

Abstract 2900 Myeloperoxidase (MPO) is a heme-containing peroxidase abundantly
expressed in neutrophils and to a lesser extent in monocytes. Enzymatically active MPO …

Rationale: Neutrophil extracellular trap (NET) formation promotes vascular damage,
thrombosis, and activation of interferon-α–producing plasmacytoid dendritic cells in …

As in human disease, macrophages (MØ) are central players in the development and
progression of experimental atherosclerosis. In this study we have evaluated the phenotype …