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Diabetes, metabolic disease, and telomere length
Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes.
Telomere length is a marker of DNA damage, which is often considered a biomarker for …
Telomere length is a marker of DNA damage, which is often considered a biomarker for …
Obesity: a perfect storm for carcinogenesis
BHL Harris, VM Macaulay, DA Harris… - Cancer and Metastasis …, 2022 - Springer
Obesity-related cancers account for 40% of the cancer cases observed in the USA and
obesity is overtaking smoking as the most widespread modifiable risk factor for …
obesity is overtaking smoking as the most widespread modifiable risk factor for …
Association between the oxidative balance score and telomere length from the National Health and Nutrition Examination Survey 1999‐2002
W Zhang, SF Peng, L Chen, HM Chen… - Oxidative medicine …, 2022 - Wiley Online Library
Purpose. Leukocyte telomere length (LTL) is an important biomarker of aging. The oxidative
balance score (OBS) is used to assess the oxidative stress‐related exposures of diet and …
balance score (OBS) is used to assess the oxidative stress‐related exposures of diet and …
Lifespan Perspective on Congenital Heart Disease Research: JACC State-of-the-Art Review
More than 90% of patients with congenital heart disease (CHD) are nowadays surviving to
adulthood and adults account for over two-thirds of the contemporary CHD population in …
adulthood and adults account for over two-thirds of the contemporary CHD population in …
Effect of long‐term caloric restriction on telomere length in healthy adults: CALERIE™ 2 trial analysis
Caloric restriction (CR) modifies lifespan and aging biology in animal models. The
Comprehensive Assessment of Long‐Term Effects of Reducing Intake of Energy …
Comprehensive Assessment of Long‐Term Effects of Reducing Intake of Energy …
Genetic evidence for causal effects of socioeconomic, lifestyle, and cardiometabolic factors on epigenetic-age acceleration
Abstract GrimAge acceleration (GrimAgeAccel) and PhenoAge acceleration
(PhenoAgeAccel) are DNA methylation-based markers of accelerated biological aging …
(PhenoAgeAccel) are DNA methylation-based markers of accelerated biological aging …
Modifiable traits, healthy behaviours, and leukocyte telomere length: a population-based study in UK Biobank
Background Telomere length is associated with risk of several age-related diseases and
cancers. We aimed to investigate the extent to which telomere length might be modifiable …
cancers. We aimed to investigate the extent to which telomere length might be modifiable …
Associations of body composition and physical activity level with multiple measures of epigenetic age acceleration
JK Kresovich, EL Garval… - American journal of …, 2021 - academic.oup.com
Epigenetic clocks use DNA methylation to estimate biological age. Whether body
composition and physical activity are associated with these clocks is not well understood …
composition and physical activity are associated with these clocks is not well understood …
An integrative study of five biological clocks in somatic and mental health
Biological clocks have been developed at different molecular levels and were found to be
more advanced in the presence of somatic illness and mental disorders. However, it is …
more advanced in the presence of somatic illness and mental disorders. However, it is …
Accelerated aging in bipolar disorder: A comprehensive review of molecular findings and their clinical implications
GR Fries, MJ Zamzow, T Andrews, O Pink… - Neuroscience & …, 2020 - Elsevier
Bipolar disorder (BD) has been associated with clinical signs of accelerated aging, which
potentially underlies its association with several age-related medical conditions, such as …
potentially underlies its association with several age-related medical conditions, such as …