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Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
Lymphoid organ-targeted nanomaterials for immunomodulation of cancer, inflammation, and beyond
Nanomaterials exhibit significant potential for stimulating immune responses, offering both
local and systemic modulation across a variety of diseases. The lymphoid organs, such as …
local and systemic modulation across a variety of diseases. The lymphoid organs, such as …
Multicomponent synthesis of imidazole-based ionizable lipids for highly efficient and spleen-selective messenger RNA delivery
W Dong, Z Li, T Hou, Y Shen, Z Guo… - Journal of the …, 2024 - ACS Publications
The spleen emerges as a pivotal target for mRNA delivery, prompting a continual quest for
specialized and efficient lipid nanoparticles (LNPs) designed to enhance spleen-selective …
specialized and efficient lipid nanoparticles (LNPs) designed to enhance spleen-selective …
H2S-Reactivating Antitumor Immune Response after Microwave Thermal Therapy for Long-Term Tumor Suppression
S Li, F Xu, X Ren, L Tan, C Fu, Q Wu, Z Chen, J Ren… - ACS …, 2023 - ACS Publications
Microwave thermal therapy (MWTT) is one of the most potent ablative treatments known,
with advantages like deep penetration, minimal invasion, repeatable operation, and low …
with advantages like deep penetration, minimal invasion, repeatable operation, and low …
Advancements in hydrogel-based drug delivery systems for the treatment of inflammatory bowel disease: a review
Y Liu, J Huang, S Li, Z Li, C Chen, G Qu, K Chen… - Biomaterials …, 2024 - pubs.rsc.org
Inflammatory bowel disease (IBD) is a chronic disorder that affects millions of individuals
worldwide. However, current drug therapies for IBD are plagued by significant side effects …
worldwide. However, current drug therapies for IBD are plagued by significant side effects …
Recent advances on emerging nanomaterials for diagnosis and treatment of inflammatory bowel disease
Inflammatory bowel disease (IBD) is a chronic idiopathic inflammatory disorder that affects
the entire gastrointestinal tract and is associated with an increased risk of colorectal cancer …
the entire gastrointestinal tract and is associated with an increased risk of colorectal cancer …
Inhibiting the cGAS-STING pathway in ulcerative colitis with programmable micelles
Ulcerative colitis is a chronic condition in which a dysregulated immune response
contributes to the acute intestinal inflammation of the colon. Current clinical therapies often …
contributes to the acute intestinal inflammation of the colon. Current clinical therapies often …
AH2S‐Generated Supramolecular Photosensitizer for Enhanced Photodynamic Antibacterial Infection and Relieving Inflammation
J Tian, B Huang, L **a, Y Zhu, W Zhang - Advanced Science, 2024 - Wiley Online Library
Photodynamic therapy (PDT) is a promising treatment against bacteria‐caused infections.
By producing large amounts of reactive oxygen species (ROS), PDT can effectively eliminate …
By producing large amounts of reactive oxygen species (ROS), PDT can effectively eliminate …
Spleen-targeted delivery systems and strategies for spleen-related diseases
Z Huang, K Sun, Z Luo, J Zhang, H Zhou, H Yin… - Journal of Controlled …, 2024 - Elsevier
The spleen, body's largest secondary lymphoid organ, is also a vital hematopoietic and
immunological organ. It is regarded as one of the most significant organs in humans. As …
immunological organ. It is regarded as one of the most significant organs in humans. As …
[HTML][HTML] Anti-inflammatory effects of dietary polyphenols through inhibitory activity against metalloproteinases
T Suzuki, T Ohishi, H Tanabe, N Miyoshi, Y Nakamura - Molecules, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are zinc-dependent metalloproteinases that play
important roles in a variety of diseases, including cancer, cardiovascular disease, diabetes …
important roles in a variety of diseases, including cancer, cardiovascular disease, diabetes …