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High-throughput screening, next generation sequencing and machine learning: advanced methods in enzyme engineering
Enzyme engineering is an important biotechnological process capable of generating
tailored biocatalysts for applications in industrial chemical conversion and biopharma …
tailored biocatalysts for applications in industrial chemical conversion and biopharma …
Recent advances of metabolic engineering strategies in natural isoprenoid production using cell factories
Covering: up to 2019 As abundant natural products, isoprenoids have many useful industrial
applications in the manufacturing of drugs, fragrances, food additives, colorants, rubber and …
applications in the manufacturing of drugs, fragrances, food additives, colorants, rubber and …
Machine-learning guided elucidation of contribution of individual steps in the mevalonate pathway and construction of a yeast platform strain for terpenoid production
The production of terpenoids from engineered microbes contributes markedly to the
bioeconomy by providing essential medicines, sustainable materials, and renewable fuels …
bioeconomy by providing essential medicines, sustainable materials, and renewable fuels …
Potential natural food preservatives and their sustainable production in yeast: terpenoids and polyphenols
X Lyu, J Lee, WN Chen - Journal of agricultural and food chemistry, 2019 - ACS Publications
Terpenoids and polyphenols are high-valued plant secondary metabolites. Their high
antimicrobial activities demonstrate their huge potential as natural preservatives in the food …
antimicrobial activities demonstrate their huge potential as natural preservatives in the food …
Recent Advances and Multiple Strategies of Monoterpenoid Overproduction in Saccharomyces cerevisiae and Yarrowia lipolytica
Monoterpenoids are an important subclass of terpenoids that play important roles in the
energy, cosmetics, pharmaceuticals, and fragrances fields. With the development of …
energy, cosmetics, pharmaceuticals, and fragrances fields. With the development of …
Metabolic engineering of microbes for monoterpenoid production
K Zhu, J Kong, B Zhao, L Rong, S Liu, Z Lu… - Biotechnology …, 2021 - Elsevier
Monoterpenoids are an important class of natural products that are derived from the
condensation of two five‑carbon isoprene subunits. They are widely used for flavouring …
condensation of two five‑carbon isoprene subunits. They are widely used for flavouring …
Plasticity engineering of plant monoterpene synthases and application for microbial production of monoterpenoids
D Lei, Z Qiu, J Qiao, GR Zhao - Biotechnology for biofuels, 2021 - Springer
Plant monoterpenoids with structural diversities have extensive applications in food,
cosmetics, pharmaceuticals, and biofuels. Due to the strong dependence on the …
cosmetics, pharmaceuticals, and biofuels. Due to the strong dependence on the …
Metabolic engineering strategies to overcome precursor limitations in isoprenoid biosynthesis
Highlights•Enhancing precursor supply is effective for improving isoprenoid
biosynthesis.•Both local and global approaches relative to the biosynthetic pathway are …
biosynthesis.•Both local and global approaches relative to the biosynthetic pathway are …
A well‐characterized polycistronic‐like gene expression system in yeast
Efficient expression of multiple genes is critical to yeast metabolic engineering for the
bioproduction of bulk and fine chemicals. A yeast polycistronic expression system is of …
bioproduction of bulk and fine chemicals. A yeast polycistronic expression system is of …
The construction and optimization of engineered yeast chassis for efficient biosynthesis of 8‐hydroxygeraniol
Y Zhang, M Yuan, X Wu, Q Zhang, Y Wang, L Zheng… - Mlife, 2023 - Wiley Online Library
Microbial production of monoterpenoid indole alkaloids (MIAs) provides a sustainable and
eco‐friendly means to obtain compounds with high pharmaceutical values. However …
eco‐friendly means to obtain compounds with high pharmaceutical values. However …