Due to the ability to regulate target metabolic pathways globally and dynamically, metabolic
regulation systems composed of transcription factors have been widely used in metabolic …

Despite enormous progress in understanding the fundamentals of bacterial gene regulation,
our knowledge remains limited when compared with the number of bacterial genomes and …

Synthetic biology continues to progress by relying on more robust tools for transcriptional
control, of which promoters are the most fundamental component. Numerous studies have …

Oxidative stress is an important and pervasive physical stress encountered by all kingdoms
of life, including bacteria. In this review, we briefly describe the nature of oxidative stress …

Transcription activation is an important checkpoint of regulation of gene expression which
occurs in response to different intracellular and extracellular signals. The key elements in …

Decades of research have probed the interplay between chromatin (genomic DNA
associated with proteins and RNAs) and transcription by RNA polymerase (RNAP) in all …

The MerR-family transcription factors (TFs) are a large group of bacterial proteins
responding to cellular metal ions and multiple antibiotics by binding within central RNA …

Promoter-specific activation of transcript initiation provides an important regulatory device in
Escherichia coli and Salmonella. Here, we describe the different mechanisms that operate …

Our knowledge of transcriptional responses to changes in nutrient availability comes
primarily from few well-studied transcription factors (TFs), often lacking an unbiased genome …

Transcription factors (TFs) modulate gene expression by regulating the accessibility of
promoter DNA to RNA polymerases (RNAPs) in bacteria. The MerR family TFs are a large …