Epidemiology and treatment of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa infections

JP Horcajada, M Montero, A Oliver, L Sorlí… - Clinical microbiology …, 2019 - Am Soc Microbiol
In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

Treatment of infections caused by extended-spectrum-beta-lactamase-, AmpC-, and carbapenemase-producing Enterobacteriaceae

J Rodríguez-Baño, B Gutiérrez-Gutiérrez… - Clinical microbiology …, 2018 - Am Soc Microbiol
Therapy of invasive infections due to multidrug-resistant Enterobacteriaceae (MDR-E) is
challenging, and some of the few active drugs are not available in many countries. For …

Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions

LS Tzouvelekis, A Markogiannakis… - Clinical microbiology …, 2012 - Am Soc Microbiol
The spread of Enterobacteriaceae, primarily Klebsiella pneumoniae, producing KPC, VIM,
IMP, and NDM carbapenemases, is causing an unprecedented public health crisis …

Fosfomycin

ME Falagas, EK Vouloumanou… - Clinical microbiology …, 2016 - Am Soc Microbiol
The treatment of bacterial infections suffers from two major problems: spread of multidrug-
resistant (MDR) or extensively drug-resistant (XDR) pathogens and lack of development of …

The “old” and the “new” antibiotics for MDR gram-negative pathogens: for whom, when, and how

I Karaiskos, S Lagou, K Pontikis, V Rapti… - Frontiers in public …, 2019 - frontiersin.org
The recent expansion of multidrug resistant and pan-drug-resistant pathogens poses
significant challenges in the treatment of healthcare associated infections. An important …

Antimicrobial Treatment of Staphylococcus aureus Biofilms

FF Tuon, PH Suss, JP Telles, LR Dantas, NH Borges… - Antibiotics, 2023 - mdpi.com
Staphylococcus aureus is a microorganism frequently associated with implant-related
infections, owing to its ability to produce biofilms. These infections are difficult to treat …

Antibiotic treatment of infections due to carbapenem-resistant Enterobacteriaceae: systematic evaluation of the available evidence

ME Falagas, P Lourida, P Poulikakos… - Antimicrobial agents …, 2014 - Am Soc Microbiol
We sought to evaluate the effectiveness of the antibiotic treatment administered for infections
caused by carbapenemase-producing Enterobacteriaceae. The PubMed and Scopus …

Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches

I Karaiskos, H Giamarellou - Expert opinion on pharmacotherapy, 2014 - Taylor & Francis
Introduction: In the era of multidrug-resistant, extensively drug-resistant (XDR) and even
pandrug-resistant Gram-negative microorganisms, the medical community is facing the …

Fosfomycin: pharmacological, clinical and future perspectives

AC Dijkmans, NV Ortiz Zacarías, J Burggraaf… - Antibiotics, 2017 - mdpi.com
Fosfomycin is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative
activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by …

[BOOK][B] The WHO AWaRe (access, watch, reserve) antibiotic book

World Health Organization - 2022 - books.google.com
There is a clear need for simple resources to improve the quality of antibiotic prescribing
globally. The AWaRe book was designed as a tool to make the antibiotics section of the …