The transportome of the malaria parasite

RE Martin - Biological Reviews, 2020 - Wiley Online Library
Membrane transport proteins, also known as transporters, control the movement of ions,
nutrients, metabolites, and waste products across the membranes of a cell and are central to …

Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle

H Ke, IA Lewis, JM Morrisey, KJ McLean, SM Ganesan… - Cell reports, 2015 - cell.com
New antimalarial drugs are urgently needed to control drug-resistant forms of the malaria
parasite Plasmodium falciparum. Mitochondrial electron transport is the target of both …

Mitochondrial tricarboxylate and dicarboxylate–tricarboxylate carriers: from animals to plants

V Dolce, AR Cappello, L Capobianco - IUBMB life, 2014 - Wiley Online Library
The citrate carrier (CiC), characteristic of animals, and the dicarboxylate–tricarboxylate
carrier (DTC), characteristic of plants and protozoa, belong to the mitochondrial carrier …

A rice gene that confers broad-spectrum resistance to β-triketone herbicides

H Maeda, K Murata, N Sakuma, S Takei, A Yamazaki… - Science, 2019 - science.org
The genetic variation of rice cultivars provides a resource for further varietal improvement
through breeding. Some rice varieties are sensitive to benzobicyclon (BBC), a β-triketone …

The mitochondrion of Plasmodium falciparum is required for cellular acetyl-CoA metabolism and protein acetylation

SC Nair, JT Munro, A Mann, M Llinás… - Proceedings of the …, 2023 - pnas.org
Coenzyme A (CoA) biosynthesis is an excellent target for antimalarial intervention. While
most studies have focused on the use of CoA to produce acetyl-CoA in the apicoplast and …

Mechanically stable solvent-free lipid bilayers in nano-and micro-tapered apertures for reconstitution of cell-free synthesized hERG channels

D Tadaki, D Yamaura, S Araki, M Yoshida, K Arata… - Scientific Reports, 2017 - nature.com
The self-assembled bilayer lipid membrane (BLM) is the basic component of the cell
membrane. The reconstitution of ion channel proteins in artificially formed BLMs represents …

Metabolic changes accompanying the loss of fumarate hydratase and malate–quinone oxidoreductase in the asexual blood stage of Plasmodium falciparum

K Rajaram, SG Tewari, A Wallqvist, ST Prigge - Journal of Biological …, 2022 - jbc.org
In the glucose-rich milieu of red blood cells, asexually replicating malarial parasites mainly
rely on glycolysis for ATP production, with limited carbon flux through the mitochondrial …

Partner-switching components PmgA and Ssr1600 regulate high-light acclimation in Synechocystis sp. PCC 6803

R Nakamura, Y Takahashi, S Tachibana… - Plant …, 2024 - academic.oup.com
Photomixotrophic g rowth A (PmgA) is a pleiotropic regulator essential for growth under
photomixotrophic and prolonged high-light (HL) conditions in the cyanobacterium …

Cell-free translation system with artificial lipid-monolayer particles as a unique tool for characterizing lipid-monolayer binding proteins

F Kuroiwa, H Suda, M Yabuki… - Bioscience …, 2024 - academic.oup.com
Methods for functional analysis of proteins specifically localizing to lipid monolayers such as
rubber particles and lipid droplets are limited. We have succeeded in establishing a system …

Application of wheat germ cell-free protein expression system for novel malaria vaccine candidate discovery

TU Arumugam, D Ito, E Takashima… - Expert review of …, 2014 - Taylor & Francis
Malaria causes about 216 million clinical cases and 0.7 million deaths annually. One
promising route to address malaria is vaccination. However, so far, not even a single …