Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Overview Systemic mastocytosis (SM) results from a clonal proliferation of abnormal mast
cells (MCs) in extra‐cutaneous organs. Diagnosis The major criterion is presence of …

It is well recognized that neuroinflammation is involved in the pathogenesis of various
neurodegenerative diseases. Microglia and astrocytes are major pathogenic components …

Mast cells (MCs) are both sensors and effectors in communication among nervous, vascular,
and immune systems. In the brain, they reside on the brain side of the blood–brain barrier …

Cells of the immune system and the central nervous system are capable of interacting with
each other. The former cell populations respond to infection, tissue injury and trauma by …

Disease overview: Systemic mastocytosis (SM) results from a clonal proliferation of
abnormal mast cells (MC) in one or more extra‐cutaneous organs. Diagnosis: The major …

Background Indolent systemic mastocytosis, including the subvariant of smouldering
systemic mastocytosis, is a lifelong condition associated with reduced quality of life …

Accumulating scientific and clinical evidence highlighted pathological hyperinflammation as
a cardinal feature of SARS-CoV-2 infection and acute COVID-19 disease. With the …

Background: Many people are unable to withstand the set point for usual vicissitudes of life
and are overwhelmed by depression, especially when there is a potential stressor like a …

Converging sources of evidence point to a role for inflammation in the development of
depression, fatigue and cognitive dysfunction. More precisely, the tryptophan (TRP) …